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The investigators aimed to show the renal damage caused by increased intra-abdominal pressure in laparoscopic surgeries and to investigate whether its reflection on NIRS would be clinically effective.The main question it aims to answer are:
Does pneumoperitoneum cause renal damage?
NRS monitoring will be performed in patients undergoing laparoscopic surgery. Preoperative and postoperative blood tests will be performed at certain hours. N-GAL, urea and creatinine values will be recorded.
Renal NIRS monitoring will be performed in patients undergoing laparoscopic cholecystectomy surgery. Age, gender, BMI, ASA scores, hemogblin/hematocrit values, intraoperative hemodynamic parameters, NIRS values, N-GAL (preoperative, 2nd hour and 24th hour), urea/creatinine (preoperative, postoperative 24th hour) values of the patients will be recorded. .
Before the general anesthesia is performed, the renal tissues of the patients will be visualized by ultrasound, the skin-renal cortex distances will be measured, and suitable patients will be included in the study. Basal rSO2 values will be recorded by placing NIRS probes under the 10-11. intercostal space in the bilateral posterior lateral flank region.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients undergoing laparoscopic cholecystectomy. | Basal rSO2 values will be recorded by placing NIRS probes under the 10-11th intercostal space in the bilateral posterior lateral flank region. Age, gender, BMI, ASA scores, Hb/Htc values, intraoperative hemodynamic parameters, NIRS values, N-GAL (preoperative, 2nd hour and 24th hour), urea/creatinine (preoperative, postoperative 24th hour) values of the patients will be recorded. . |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| NIRS | Device | Renal perfusion will be evaluated with NIRS |
|
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of renal damage caused by pneumoperitoneum with N-GAL by blood test | Taking a blood test to evaluation N-GAL | During laparoscopic cholecystectomy operation and within 24 hours postoperative |
| Evaluation of renal damage caused by pneumoperitoneum with urea/creatinin by blood test | Taking a blood test to evaluation urea/creatinine values | During laparoscopic cholecystectomy operation and within 24 hours postoperative |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who undergoing elective laparoscopic cholecystectomi surgery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Savaş Altınsoy, MD | Contact | 0905332257104 | savasaltinsoy@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Savaş Altınsoy, MD | Ankara Etlik City Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Anesthesiology and Reanimation, University of Health Sciences, Diskapi Yıldırım Beyazit Training and Research Hospital | Ankara | 06450 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32651617 | Background | Caliskan E, Sanal Bas S, Onay M, Kilic Y, Kayhan Erdogan G, Tokar B. Evaluation of renal oxygenization in laparoscopic pediatric surgery by near infrared spectroscopy. Pediatr Surg Int. 2020 Sep;36(9):1077-1086. doi: 10.1007/s00383-020-04709-w. Epub 2020 Jul 10. |
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| ID | Term |
|---|---|
| D011027 | Pneumoperitoneum |
| ID | Term |
|---|---|
| D010532 | Peritoneal Diseases |
| D004066 | Digestive System Diseases |
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blood sample