Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of this study is to investigate the relationship between different ultrasonographic indices used in patients with carpal tunnel syndrome and clinical parameters.
The main questions it aims to answer are:
Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy and the main mechanism is compression of the median nerve under the transverse ligament at the wrist level. In CTS, neuropathic complaints such as numbness, burning and tingling in the palmar face of the first two fingers, which are the innervation area of the median nerve, and fatigue in the hand are the most common symptoms. In the diagnosis of CTS, the diagnosis is made electrodiagnostically along with typical clinical findings. However, in recent years, ultrasound has become one of the most preferred methods in the diagnosis of CTS because it is non-invasive, rapid and correlates with electrodiagnostic methods. Diameter, cross-sectional area and echogenicity of the median nerve at the carpal tunnel entrance are the most frequently evaluated parameters in ultrasonographic examination. In different studies, it is aimed to increase the power of ultrasonography in the diagnosis of CTS with various indices created in addition to standardized measurements. The most commonly used ultrasonographic indices, which have been shown to be correlated with electrodiagnostic diagnostic methods, are the wrist-forearm median nerve cross-sectional area ratio, the ratio of median nerve cross-sectional area to carpal tunnel area at the carpal tunnel entry level, and echogenicity assessment. Although the relationship of these indexes, which are reported to have sufficient diagnostic sensitivity and specificity, with the patient's clinical complaints is shown on a measurement basis, there is not enough data on the comparison of different formulas and their correlation with the patient's clinical complaints, including neuropathic pain.Based on this, this study aimed to investigate the relationship between ultrasonographic indices used in patients diagnosed with CTS and clinical parameters.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient group | Patients with carpal tunnel syndrome |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nerve ultrasound | Diagnostic Test | Ultrasonographic evaluation of the median nerve at the carpal tunnel and adjacent levels |
|
| Measure | Description | Time Frame |
|---|---|---|
| median nerve ultrasound | Median nerve cross-sectional area measurement at the level of the carpal tunnel (mm²) | 3 months |
| median nerve ultrasound | Median nerve echogenicity at the level of the carpal tunnel (%) | 3 months |
| median nerve ultrasound | Median nerve cross-sectional area measurement at the level of the carpal tunnel inlet (mm²) | 3 months |
| median nerve ultrasound | Median nerve cross-sectional area measurement at the level of the carpal tunnel outlet (mm²) | 3 months |
| median nerve ultrasound | Median nerve cross-sectional area measurement at the level of the pronator quadratus (mm²) | 3 months |
| median nerve ultrasound | vertical thickness measurement of the median nerve at the level of the carpal tunnel | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Visual analog scale | The visual analog scale (VAS) is a validated subjective measure for pain, scored in the 0-10 range (0:no pain; 10: worst pain). | 3 months |
| Upper extremity nerve conduction studies |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Patients with diagnosed CTS
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Emre Ata, Assoc.Prof | Saglik Bilimleri Universitesi | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Saglik Bilimleri Universitesi | Istanbul | Uskudar | Turkey (Türkiye) |
Dataset sharing is not planned
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D002349 | Carpal Tunnel Syndrome |
| ID | Term |
|---|---|
| D020423 | Median Neuropathy |
| D020422 | Mononeuropathies |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D000092184 | Nerve Conduction Studies |
| ID | Term |
|---|---|
| D003943 | Diagnostic Techniques, Neurological |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D004568 | Electrodiagnosis |
Not provided
Not provided
Not provided
Not provided
Not provided
| Nerve conduction studies | Diagnostic Test | Upper extremity nerve conduction studies including median-ulnar sensory and motor responses |
|
Bilateral median and ulnar sensorimotor latency measurement (msec)
| 3 months |
| Upper extremity nerve conduction studies | Bilateral median and ulnar motor amplitude measurement (mV) | 3 months |
| Upper extremity nerve conduction studies | Bilateral median and ulnar sensory amplitude measurement ( µV) | 3 months |
| Upper extremity nerve conduction studies | Bilateral median and ulnar sensorimotor conduction velocity measurement (m/sn) | 3 months |
| Self Leeds Assessment of Neuropathic Symptoms and Sign | Self Leeds Assessment of Neuropathic Symptoms and Sign is a 7-question scale used to define pain of neuropathic origin and a score of 12 points or more is in favor of the presence of neuropathic pain.The total score ranges from 0 to 24, and higher scores are associated with an increase in neuropathic complaints. | 3 months |
| Boston Carpal Tunnel Questionnaire | he Boston Carpal Tunnel Score is a patient-reported questionnaire that examines symptom severity and overall functional status of patients with carpal tunnel syndrome. Two subscores are calculated: Symptom Severity Scale (SSS) and Functional Status Scale (FSS); SSS score range is 11-55, FSS score range is 8-40 and higher scores indicate worse symptoms or function. | 3 months |
| hand grip strength | Grip strength is a measure of muscle strength or the maximum force/tension produced by one's forearm muscles and is measured with a hand dynamometer. | 3 months |
| D009422 | Nervous System Diseases |
| D009408 | Nerve Compression Syndromes |
| D012090 | Cumulative Trauma Disorders |
| D013180 | Sprains and Strains |
| D014947 | Wounds and Injuries |