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The purpose of this study is to evaluate the vestibular effects of gamma-knife radiosurgery, as part of the treatment of vestibular schwannoma.
Vestibular schwannoma is a benign tumor located on the vestibulocochlear nerve. It represents 6 to 8% of intracranial tumors, 80% of ponto-cerebral angle tumors and its frequency is 13 cases per million inhabitants per year.
The main symptoms related to the development of vestibular schwannoma are unilateral deafness of perception, unilateral tinnitus, unilateral vestibular deficit vertigo, facial paralysis.
Management is divided into 3 options: monitoring, surgery and gamma-knife radiosurgery.
This study will focus on gamma-knife radiosurgery. The objective of this treatment is to stabilize the evolution of schwannoma.
This study aims to describe the vestibular effects of radiosurgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Radiosurgery | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vestibular exam | Other | Interrogation, videonystagmoscopy, videonystagmography, video-head-impulse-test |
|
| Measure | Description | Time Frame |
|---|---|---|
| Description of vestibular function with videonystagmography before gamma-knife radiosurgery, as part of the treatment of vestibular schwannoma. | Videonystagmography: Results of caloric tests = Intervestibular deficit (in percentage) | 1 month before gamma-knife radiosurgery |
| Description of vestibular function with vidéonystagmoscopy before gamma-knife radiosurgery, as part of the treatment of vestibular schwannoma. | Videonystagmography: Results of caloric tests = Intervestibular deficit (in percentage) | After gamma-knife radiosurgery at 6 month or 12 month or 18 month or 2 years or 3 years depending on the history of the treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Description of vestibular symptoms before gamma-knife radiosurgery as part of the treatment of vestibular schwannoma. | Dizziness Handicap Inventoryquestionnaire (DHI questionnaire) | 1 month before gamma-knife radiosurgery |
| Description of vestibular symptoms after gamma-knife radiosurgery as part of the treatment of vestibular schwannoma. |
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Inclusion Criteria :
Exclusion Criteria :
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mylene ABISSE, MD | Contact | +33381218988 | mabisse@chu-besancon.fr | |
| POZET Astrid | Contact | +33381218988 | apozet@chu-besancon.fr |
| Name | Affiliation | Role |
|---|---|---|
| DAMON Veronique, MD | CHU de Besançon | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Besançon | Recruiting | Besançon | France |
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| ID | Term |
|---|---|
| D009464 | Neuroma, Acoustic |
| D009442 | Neurilemmoma |
| ID | Term |
|---|---|
| D018358 | Neuroendocrine Tumors |
| D017599 | Neuroectodermal Tumors |
| D009373 | Neoplasms, Germ Cell and Embryonal |
| D009370 | Neoplasms by Histologic Type |
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Prognostic cohort study
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Dizziness Handicap Inventoryquestionnaire (DHI questionnaire) |
| After gamma-knife radiosurgery at 6 month or 12 month or 18 month or 2 years or 3 years depending on the history of the treatment |
| D009369 | Neoplasms |
| D009463 | Neuroma |
| D018317 | Nerve Sheath Neoplasms |
| D009380 | Neoplasms, Nerve Tissue |
| D003390 | Cranial Nerve Neoplasms |
| D009423 | Nervous System Neoplasms |
| D009371 | Neoplasms by Site |
| D010524 | Peripheral Nervous System Neoplasms |
| D000160 | Vestibulocochlear Nerve Diseases |
| D012181 | Retrocochlear Diseases |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D010039 | Otorhinolaryngologic Neoplasms |
| D003389 | Cranial Nerve Diseases |
| D009422 | Nervous System Diseases |