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| ID | Type | Description | Link |
|---|---|---|---|
| 2023-A01356-39 | Other Identifier | IDRCB |
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In this study, the poly vaccination of military personnel prior to deployment will be analyzed in terms of central, peripheral and long-lasting changes in innate immunity.
Analysis of monocyte immune training induced by vaccination will provide a better understanding of the indirect effects of vaccination and their persistence over time.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sampling and survey group | This group will complete questionnaires and participate in sample collection. |
| |
| Survey group | This group will only complete questionnaires |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Blood and saliva sampling | Other | Collecting blood and saliva sample |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Monocytes' functional reprogramming | describing the functional reprogramming of monocytes following vaccination sessions among military personnel prior and after deployment | 11 months |
| Measure | Description | Time Frame |
|---|---|---|
| Identify immune signatures | Identifying immune signatures by comparing the functional reprogramming of monocytes by different vaccines and co vaccinations schemes | 11 months |
| Time persistence | Assess the persistence over time of the effects by follow-up after return from mission |
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Inclusion Criteria:
Exclusion Criteria:
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The study population is composed by healthy subjects which have to receive a vaccine update in order to be deployed
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| ID | Term |
|---|---|
| D000093742 | Breakthrough Infections |
| ID | Term |
|---|---|
| D007239 | Infections |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D001800 | Blood Specimen Collection |
| D011795 | Surveys and Questionnaires |
| ID | Term |
|---|---|
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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Blood sample and saliva sample
| Survey |
| Other |
Collecting data on infectious diseases during the study period |
|
| 11 months |
| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |