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This randomized clinical trial carried out on 60 Brazilian men, aged 18 to 65, with mild or moderate androgenetic alopecia. Two techniques for administering dutasteride will be compared, injected by syringes or needles or by needling through tattoo machines.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MESOTHERAPY (INJECTIONS WITH SYRINGE AND NEEDLE) | Active Comparator | After the anesthetic block, dutasteride will be injected using syringes and needles into the area of alopecia. |
|
| MMP (INJECTIONS WITH TATTOO MACHINE) | Experimental | After the anesthetic block, dutasteride will be injected through needling performed by a tattoo machine in the area of alopecia. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MESOTHERAPY (INJECTIONS WITH SYRINGE AND NEEDLE) | Procedure | After the anesthetic block, dutasteride will be injected using syringes and needles into the area of alopecia. |
|
| Measure | Description | Time Frame |
|---|---|---|
| HAIR DENSITY | analysis of hair density (number of follicles) per square centimeter using Trichoscale software (fotofinder) and clinical photographs. | 1 year |
| HAIR THICKNESS | measurement of the thickness of hair shafts using Trichoscale software (fotofinder) | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Sexual effects | Assessment of sexual adverse effects (sexual impotence or decreased libido) through Likert questionnaire: The answer will be dichotomous, did you feel any sexual effects (impotence or decreased libido during your treatment? Yes or no? | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
yes
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| SAMIR ARBACHE, PhD | Contact | 12 981221011 | samir.arbache@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinica Dermatologica Arbache | Recruiting | São José dos Campos | São Paulo | 12245-760 | Brazil |
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This is a randomized study carried out on 60 men. Two techniques for administering dutasteride will be compared, injected by syringes or needles (mesotherapy) or needling using the MMP technique (through tattoo machines)
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| MMP (INJECTIONS WITH A TATTOO MACHINE) | Procedure | After the anesthetic block, dutasteride will be injected through needling performed by a tattoo machine in the area of alopecia. |
|
| ID | Term |
|---|---|
| D000505 | Alopecia |
| ID | Term |
|---|---|
| D007039 | Hypotrichosis |
| D006201 | Hair Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D057748 | Mesotherapy |
| D007267 | Injections |
| D013594 | Syringes |
| D009339 | Needles |
| D020782 | Matrix Metalloproteinases |
| ID | Term |
|---|---|
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D003357 | Cosmetic Techniques |
| D007279 | Injections, Subcutaneous |
| D004333 | Drug Administration Routes |
| D004358 | Drug Therapy |
| D004864 | Equipment and Supplies |
| D008666 | Metalloendopeptidases |
| D010450 | Endopeptidases |
| D010447 | Peptide Hydrolases |
| D006867 | Hydrolases |
| D004798 | Enzymes |
| D045762 | Enzymes and Coenzymes |
| D045726 | Metalloproteases |
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