Vagal Nerve Stimulation as an Alternative Therapy for Premature Ventricular Contractions

Vagal Nerve Stimulation as an Alternative Therapy for Premature Ventricular Contractions

Prospective randomized control pilot study

The primary aims of this investigator initiated study is :

Aim 1: to assess the ability of non-invasive vagal nerve stimulation to suppress Premature Ventricular Contractions and Aim 2: to compare the efficacy of Lower-level Tragus stimulation and Heart rate variability- Biofeedback in suppression of Premature Ventricular Contractions.

Inclusion Criteria:

• Normal Left Ventricular systolic function
• Frequent PVCs

Exclusion Criteria:

• Current use of any (I and/or III) antiarrhythmic medication
• Contraindication to use beta blockers and non-dihydropyridine calcium channel blockers
• Complete Atrioventricular block and pacemaker dependent
• Ongoing uncontrolled hypertension with systolic Blood Pressure> 180
• Family history of dilated Cardiomyopathy in a first degree relative
• Alcohol use disorder or illicit drug use
• Actively being treated Atrial fibrillation/ Flutter with Rapid Ventricular Response
• Moderate to severe valve disorders
• Patient with shortwave/microwave therapy equipment