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| Name | Class |
|---|---|
| Dartmouth College | OTHER |
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The purpose of this study is to determine whether people with MCI (Mild Cognitive Impairment) and healthy comparison subjects differ with respect to their ability to hear soft sounds and how their brain understands and processes sound. The investigators are also evaluating, within those with MCI, whether the hearing tests are associated with neurocognitive functioning. The investigators are interested in learning whether changes in cognition in those with MCI can be detected using tests of how the brain processes sound. The investigators hypothesize that participants with MCI will score worse on both hearing tests and neurocognitive tests than participants without MCI. Participants are asked to complete multiple types of hearing tests, take a series of neurocognitive tests, and complete a few questionnaires.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MCI | Participants diagnosed with or suspected to have MCI | ||
| Control | Participants without MCI |
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| Measure | Description | Time Frame |
|---|---|---|
| Hearing-in-Noise Test Performance | The performance for Hearing in Noise Tests (HINT) between energetic masking and 2-talker informational masking (IM). Performance will be measured by the lowest signal-to-noise ratio (volume at which sentences are presented compared to background noise volume) that can be heard by the participant. | 1 time point (takes 15 minutes) |
| Triple Digit in Noise Test Performance | Performance for the behavioral Triple Digit (TDT) between energetic masking and 2-talker informational masking (IM). Performance will be measured by the lowest signal-to-noise ratio (volume at which digits are presented compared to background noise volume) that can be heard by the participant. | 1 time point (takes 15 minutes) |
| Size of auditory neural response in background noise | The change in amplitude of neural response between energetic masking and 2-talker informational masking (IM). | 1 time point (takes 45 minutes) |
| Timing of auditory neural response in background noise | The change in latency of neural response between energetic masking and 2-talker informational masking (IM). | 1 time point (takes 45 minutes) |
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Inclusion Criteria:
Exclusion Criteria:
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The community in and around Lebanon, NH and patients from DHMC.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Samantha Leigh, BS | Contact | 5408195715 | samantha.m.leigh@dartmouth.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Space Medicine Lab at Dartmouth-Hitchcock Medical Center | Recruiting | Lebanon | New Hampshire | 03756 | United States |
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| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
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