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This study aims to retrospectively and prospectively collect clinical and biological specimen data from patients with cardiac tumors who meet the inclusion and exclusion criteria. Various techniques, including general molecular biology analysis and multi-omics analysis, will be used to construct a prognostic model for cardiac tumors.
This study aims to construct a retrospective-prospective long-term follow-up cohort and management system for cardiac tumors through a multi-centre collaborative network. The duration of the study will be divided into retrospective and prospective components. The retrospective study will collect cases of cardiac tumors from 2003-2022; the prospective study is expected to collect cases of cardiac tumors from 2022-2030. The study is expected to assess the disease characteristics, progression patterns, clinical features, natural course and long-term prognosis of cardiac tumors.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cardiac myxoma group | patients who are diagnosed as cardiac myxoma | ||
| Cardiac fibroma group | patients who are diagnosed as cardiac fibroma | ||
| Cardiac lipoma group | patients who are diagnosed as cardiac lipoma | ||
| Cardiac hemangioma group | patients who are diagnosed as cardiac hemangioma | ||
| Cardiac malignant tumor group | patients who are diagnosed as cardiac malignant tumor |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in the incidence of MACCE | MACCE (major adverse cardiac and cerebrovascular events) including all-cause death, myocardial infarction, coronary revascularization surgery and stroke. The MACCE will be assessed from the medical records. | 1, 3, 6, 12, 24, 36, 48, and 60 months after enrollment. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in the incidence of all-cause death | All-cause death diagnosed by clinical doctors will be assessed from the medical records | 1, 3, 6, 12, 24, 36, 48, and 60 months after enrollment. |
| Change in the incidence of myocardial infarction |
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Inclusion Criteria:
Exclusion Criteria:
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All patients must meet at least one of the following diagnostic criteria for cardiac neoplasms: 1. Cardiac myxoma group; 2. Cardiac fibroma group; 3. Cardiac lipoma group; 4. Cardiac hemangioma group; 5. Cardiac undifferentiated sarcoma; 6. Cardiac angiosarcoma group; 7. Cardiac rhabdomyosarcoma group; 8. Cardiac lymphoma group; 9. Cardiac metastasis group; 10. Other cardiac tumors group.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Guoliang Li | Contact | +8613759982523 | liguoliang_med@163.com | |
| Yang Yan | Contact | +8613259882601 | yangyan3@xjtu.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Guoliang Li | First Affiliated Hospital Xi'an Jiaotong University | Principal Investigator |
| Yang Yan | First Affiliated Hospital Xi'an Jiaotong University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| First Affiliated Hospital of Xi'an Jiantong University | Recruiting | Xi'an | Shaanxi | 710061 | China |
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| ID | Term |
|---|---|
| D006338 | Heart Neoplasms |
| ID | Term |
|---|---|
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D006331 | Heart Diseases |
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Myocardial infarction diagnosed by clinical doctors will be assessed from the medical records
| 1, 3, 6, 12, 24, 36, 48, and 60 months after enrollment. |
| Change in the incidence of coronary revascularization surgery | Coronary revascularization surgery completed by clinical doctors will be assessed from the medica records | 1, 3, 6, 12, 24, 36, 48, and 60 months after enrollment. |
| Change in the incidence of stroke | Stroke diagnosed by clinical doctors will be assessed from the medical records | 1, 3, 6, 12, 24, 36, 48, and 60 months after enrollment. |
| D002318 |
| Cardiovascular Diseases |