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The main purpose of this study is to establish a frailty automatic evaluation index "AI frailty index" based on artificial intelligence multi-modal non-contact monitoring information analysis. At the same time, the study will explore the correlation between ' AI weakness index ' and perioperative and long-term prognosis and quality of life.
This is a prospective cohort study. Patients who undergoes elective cardiac surgery will be enrolled. We collect frailty scales, clinical information and multi-modal, non-contact monitoring information during hospitalization. One-year follow-up will be done. The non-contact monitoring information are used to predict the frailty scales to establish and validate an AI-based frailty assessment model "AI frailty index". The AI frailty index will be further used to predict perioperative and long-term outcomes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| AI frailty index establishment group | Individuals who undergo elective cardiac surgury |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No intervention | Other | No intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| One-dimensional matrix vector composed of five frailty scale results | Consisting of five frailty scales: Edmonton frailty scale, FRAIL frailty scale, Fried frailty scale, Clinical frailty scale, and SPPB | Before and after surgery, up to 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| 30-day adverse events | Including death, readmission, stroke, myocardial infarction, renal insufficiency or renal failure, dialysis, atrial fibrillation, peripheral vascular embolism, bleeding events, heart failure | 30 days post operative |
| 1-year adverse events |
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Inclusion Criteria:
Exclusion Criteria:
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Patient aged 18 years or older, undergoing elective cardiac surgery.
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| Name | Affiliation | Role |
|---|---|---|
| Shen Lin, MD, PhD | Chinese Academy of Medical Sciences, Fuwai Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fuwai hospital | Beijing | Beijing Municipality | 100032 | China |
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| ID | Term |
|---|---|
| D000073496 | Frailty |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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Including death, readmission, stroke, myocardial infarction, renal insufficiency or renal failure, dialysis, atrial fibrillation, peripheral vascular embolism, bleeding events, heart failure |
| 1 year post operative |
| EQ-5D score | The score of EQ-5D questionnaire | 1 year post operative |
| QOR-15 score | The score of QOR-15 questionnaire | 1 year post operative |
| Edmonton frailty scale score | The Edmonton frailty scale consists of 11 items for a composite score of 0 to 17, and higher scores mean a worse outcome. | 1 year post operative |
| FRAIL frailty scale score | The FRAIL frailty scale consists of 5 items, with 3 of 5 required to diagnose frailty. | 1 year post operative |
| Fried frailty scale score | The Fried frailty scale consists of 5 items, with 3 of 5 required to diagnose frailty. | 1 year post operative |
| Clinical frailty scale score | The Clinical frailty scale is scored 1 to 9 based on a semiquantitative evaluation of the patient's symptoms, mobility, inactivity, exhaustion, and disability for basic activities of daily living and instrumental activities of daily living, and higher scores mean a worse outcome. | 1 year post operative |
| Short Physical Performance Battery scale score | The Short Physical Performance Battery scale consists of 3 physical tests, with each scored 0 to 4 for a composite score of 0 to 12, and higher scores mean a better outcome. | 1 year post operative |
| Perioperative adverse events | Including all cause death, stroke, renal insufficiency, deep sternal wound infection, and reoperation | From surgery to discharge, up to 7 days |
| Area under receiver operating curve (AUC) | Area under receiver operating curve of algorithm in predicting frailty scales and outcomes | At the end of follow-up (1 mouth) |