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Clinical trials was used to compare the effect of peppermint inhalation and Swedish massage on chemotherapy induced-nausea and vomiting in children with leukemia. the main research hypotheses are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group | No Intervention | Children with leukemia received routine nursing and hospital care for management of chemotherapy induced nausea and vomiting (antiemetic medications only). | |
| Peppermint Inhalation Group | Experimental | Children with leukemia received the inhalation of essential oil of peppermint 2% in addition to routine nursing and hospital care for management of chemotherapy induced nausea and vomiting. |
|
| Swedish Massage Group: | Experimental | Children with leukemia received the Swedish massage therapy in addition to routine nursing and hospital care for management of chemotherapy induced nausea and vomiting. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Peppermint Inhalation | Behavioral | The researcher applied two drops (0,2ml) of 2% essential oil of peppermint on a piece of cotton. Then, each child was instructed to take three breaths of the essence that had been put on a piece of cotton before starting chemotherapy session with three minutes. In addition, the piece of cotton with peppermint essence was kept at bed side table to use by child as needed throughout the chemotherapy session. Inhalation of peppermint essence was applied for three consecutive chemotherapy sessions. |
| Measure | Description | Time Frame |
|---|---|---|
| Experience of anticipatory nausea | Yes/No | assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions |
| Worst of anticipatory nausea | No/Mild/Moderate/severe/intolerable | assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions |
| Duration of anticipatory nausea | /Minutes | assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions |
| Frequency of anticipatory nausea | once/twice/ three times and more | assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions |
| Experience of anticipatory vomiting | Yes/No | assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions |
| Worst of anticipatory vomiting | No/Mild/Moderate/severe/intolerable | assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions |
| Amount of anticipatory vomiting | Small/ Moderate/ Large | assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions |
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| Measure | Description | Time Frame |
|---|---|---|
| Child's age | years | Before data collection |
| Gender | male/female | Before data collection |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Eman Arafa Badr | Alexandria | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Sowmiya Rajendran, Ruthrani Princely J, Kanchana S, Celina D., Effectiveness of Swedish Massage on the Level of Chemotherapy Induced Nausea and Vomiting (CINV) Among Children with Cancer at a Selected Hospital in North India, ICCRJNR, Jul - Dec 2016, 1(2): 20-38. | ||
| 29947285 | Background | Evans A, Malvar J, Garretson C, Pedroja Kolovos E, Baron Nelson M. The Use of Aromatherapy to Reduce Chemotherapy-Induced Nausea in Children With Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial. J Pediatr Oncol Nurs. 2018 Nov/Dec;35(6):392-398. doi: 10.1177/1043454218782133. Epub 2018 Jun 27. | |
| Background | El-SayedYousef, Y., Zaki, N. A., AsmaaAbd-Alasis, Abdel-RazikSayed, H., & Elsayed, F. (2018). Effect of Therapeutic Massage on nausea and vomitingamong Children with Leukemia following Chemotherapy. | ||
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| ID | Term |
|---|---|
| D007938 | Leukemia |
| D009325 | Nausea |
| D014839 | Vomiting |
| ID | Term |
|---|---|
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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| Swedish Massage | Behavioral | Children were received Swedish massage therapy for twenty minutes prior to chemotherapy session in a private and special room with effleurage, petrissage, friction, and tapotement and vibration movements for three consecutive chemotherapy sessions. The researcher applied facilitating olive oil in hands and pre warmed before applying massage. The massage technique was applied in prone position with mild to moderate pressure with guidance by the child's feedback and tolerance by using non-scented olive oil. Children's privacy was considered. |
|
| Frequency of anticipatory vomiting | once/ twice/ three times and more. | assessed immediately before chemotherapy administration for three consecutive chemotherapy sessions |
| Experience of acute nausea . | Yes/no. | First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study. |
| Worst of acute nausea . | No/Mild/Moderate/severe/intolerable | First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study. |
| Duration of acute nausea . | /hours. | Frst 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study. |
| Frequency of acute nausea . | once/ twice/ three times and more. | First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study. |
| Experience of acute vomiting. | Yes/No. | First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study. |
| Worst of acute vomiting. | No/Mild/Moderate/severe/intolerable | First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study. |
| Amount of acute vomiting. | Small/ Moderate/ large | First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study. |
| Frequency of acute vomiting. | once/ twice/ three times and more. | First 24 hours after first chemotherapy administration of study. Assessed within the first 24 hours after second chemotherapy administration of study. Assessed within the first 24 hours after third chemotherapy administration of study. |
| Experience of delayed nausea. | Yes/ No. | On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration. |
| Worst of delayed nausea. | No/Mild/Moderate/severe/intolerable | On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration. |
| Duration of delayed nausea. | /hours. | On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration. |
| Frequency of delayed nausea. | once/ twice/ three times and more. | On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration. |
| Experience of delayed vomiting. | Yes/ No. | On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration. |
| Worst of delayed vomiting. | No/Mild/Moderate/severe/intolerable | On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration. |
| Amount of delayed vomiting. | Small/ Moderate/ large | On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration. |
| Frequency of delayed vomiting. | once/ twice/ three times and more. | On second and third days after first chemotherapy administration.On second and third days after second chemotherapy administration. On second and third days after third chemotherapy administration. |
| Residence | rural/urban | Before data collection |
| Level of education | kinder garden/primary | Before data collection |
| Onset of the disease | months | Before data collection |
| Type of leukemia | Acute Lymphoblastic Leukemia / Acute Myeloid Leukemia/ Chronic Lymphocytic Leukemia / Chronic Myeloid Leukemia | Before data collection |
| Prescribed chemotherapy medications | Methotrexate / cytarabine | Before data collection |
| Antiemetics prescribed medications | Ondansetron | Before data collection |
| Ahmad, M. (2016). Tool Development to Assess Nausea and Vomiting Among Patients Receiving Chemotherapy. International Journal of Cancer and Oncology, 3(1), 1-5. https://doi.org/10.15436/2377-0902.16.031 |
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |