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The aim of this study was to assess the EATT and the related factors in patients with AS and to compare the results with that of the healthy controls'
The aim of this study was to investigate the epicardial adipose tissue thickness (EATT) and the related factors in patients with ankylosing spondylitis (AS) and to compare the results with those of the healthy controls. This cross-sectional study comprised thirty patients diagnosed with AS based on the modified New York criteria. The control group consisted of 31 healthy volunteers. Demographic characteristics were recorded. EATT was measured via transthoracic echocardiography. Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Ankylosing Spondylitis Disease Activity Score (ASDAS), Ankylosing Spondylitis Quality of Life (ASQoL), International Physical Activity Questionnaire Short Form (IPAQ-Short Form) were used. Functional capacity assessment was conducted using the six-minute walk test (6MWT).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ankylosing spondylitis group | Thirty patients with AS according to the modified New York criteria were included in this cross-sectional study. |
| |
| Healthy volunteers | Control group was consisted of 31 healthy volunteers |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| epicardial adipose tissue thickness | Diagnostic Test | EATT measured via transthoracic echocardiography |
|
| Measure | Description | Time Frame |
|---|---|---|
| Epicardial adipose tissue thickness | Epicardial adipose tissue thickness is measured via transthoracic echocardiography | through study completion, an average of 5 months |
| Measure | Description | Time Frame |
|---|---|---|
| Bath Ankylosing Spondylitis Disease Activity Index | The index indicates that disease activity of AS patients. Higher scores indicate that higher activity | through study completion, an average of 5 months |
| Bath Ankylosing Spondylitis Functional Index |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with AS that came to Istanbul Physical Medicine and Rehabilitation Education and Research Hospital outpatient clinic between August 2015 and January 2016
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| Name | Affiliation | Role |
|---|---|---|
| Nur Kesiktas, MD, Prof | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul Physical Medicine Rehabilitation Training and Research Hospital | Istanbul | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29479952 | Result | Keresztesi AA, Asofie G, Simion MA, Jung H. Correlation between epicardial adipose tissue thickness and the degree of coronary artery atherosclerosis. Turk J Med Sci. 2018 Feb 23;48(1):40-45. doi: 10.3906/sag-1604-58. | |
| 11427222 | Result | Taguchi R, Takasu J, Itani Y, Yamamoto R, Yokoyama K, Watanabe S, Masuda Y. Pericardial fat accumulation in men as a risk factor for coronary artery disease. Atherosclerosis. 2001 Jul;157(1):203-9. doi: 10.1016/s0021-9150(00)00709-7. |
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there is no plan to share any data
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| ID | Term |
|---|---|
| D013167 | Spondylitis, Ankylosing |
| D050197 | Atherosclerosis |
| ID | Term |
|---|---|
| D000089183 | Axial Spondyloarthritis |
| D025242 | Spondylarthropathies |
| D025241 | Spondylarthritis |
| D013166 | Spondylitis |
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The index helps to evaluate disease activity of AS patients. High scores indicate that worse functional status.
| through study completion, an average of 5 months |
| Bath Ankylosing Spondylitis Metrology Index | The index helps to evaluate spinal mobility of AS patients. Higher scores indicate more limited mobility. | through study completion, an average of 5 months |
| Ankylosing Spondylitis Disease Activity Score | This score is used to evaluate disease activity of AS patients. Higher scores indicate that higher activity. | through study completion, an average of 5 months |
| Six minute walk test | This test is used to evaluate the patient's functional capacity. In case of low functional capacity, lower scores are observed. Higher scores indicate that higher activity. | through study completion, an average of 5 months |
| Ankylosing Spondylitis Quality of Life | it is used for evaluate quality of life of AS patients. A lower score indicates better quality of life | through study completion, an average of 5 months |
| International Physical Activity Questionnaire Short Form | it is used for evaluate patient's physical activity. Scoring a high level of physical activity on the IPAQ means your physical activity levels equate to approximately one hour of activity per day or more at least a moderate intensity activity level. | through study completion, an average of 5 months |
| 14581396 | Result | Mazurek T, Zhang L, Zalewski A, Mannion JD, Diehl JT, Arafat H, Sarov-Blat L, O'Brien S, Keiper EA, Johnson AG, Martin J, Goldstein BJ, Shi Y. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation. 2003 Nov 18;108(20):2460-6. doi: 10.1161/01.CIR.0000099542.57313.C5. Epub 2003 Oct 27. |
| D013122 |
| Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D000844 | Ankylosis |
| D007592 | Joint Diseases |
| D001168 | Arthritis |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |