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| Name | Class |
|---|---|
| Tiny Blue Dot Foundation | OTHER |
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This study will examine how doing heated yoga or non-heated yoga affects depression.
The purpose of this study is to investigate the effects of heated and non-heated yoga on depressive symptoms. Previous research trials using heated and non-heated yoga interventions have shown promising results for reducing depression and its related outcomes. However, no studies have directly compared the effects of heated vs. non-heated yoga for depression. The researchers aim to address this gap by conducting a non-inferiority trial comparing heated yoga and non-heated yoga interventions to improve depressive symptoms. Both the heated and non-heated yoga interventions will be conducted in-person by certified yoga instructors. Eligible participants will be adults who do not regularly practice yoga or meditation and are experiencing moderate levels of depression. Assessments will be conducted at baseline, mid-treatment, post-treatment, and follow-up using a secure data capture system.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Heated Yoga | Experimental | The heated (i.e., ~105°F with 40% humidity) yoga will be 90 minutes long and consist of 26 Hatha yoga postures and 2 breathing exercises. The class starts with standing postures for approximately 45-50 minutes, followed by a 2-minute savasana (or corpse pose on the floor) and the remainder of the 90-minute class is completed on the mat. All yoga teachers will be heated yoga certified. |
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| Non-heated Yoga | Active Comparator | The non-heated (i.e., room temperature < 80°F) yoga will be 90 minutes long and consist of 26 Hatha yoga postures and 2 breathing exercises. The class starts with standing postures for approximately 45-50 minutes, followed by a 2-minute savasana (or corpse pose on the floor) and the remainder of the 90-minute class is completed on the mat. All yoga teachers will be heated yoga certified. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Heated Yoga | Behavioral | Heated yoga described in arm/group description |
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| Measure | Description | Time Frame |
|---|---|---|
| Patient Health Questionnaire-9 (PHQ-9) | This measure is a 9-item self-report questionnaire that is widely used to assess depression symptom severity. PHQ-9 scores range from 0 to 27. A PHQ-9 score ≥10 has a sensitivity of 88% and a specificity of 88% for major depression. PHQ-9 scores of 5, 10, 15, and 20 represented mild, moderate, moderately severe, and severe depression, respectively. | Weeks 0, 4, 8, and 20 |
| Measure | Description | Time Frame |
|---|---|---|
| The World Health Organization-5 Well-Being Index (WHO-5) | This measure is a 5-item self-report questionnaire with positively-worded statements related to positive mood, vitality, and general interest over the prior two weeks. The WHO-5 is reliable, has shown strong construct validity as a measure of general quality of life, and is sensitive to change. The WHO-5 has a score range of 0 to 25, with higher scores indicating better wellbeing. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Maren Nyer, PhD | Contact | 617-726-8895 | mnyer@mgh.harvard.edu | |
| Louisa Sylvia, PhD | Contact | 617-726-5855 | lsylvia2@mgh.harvard.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Orange Door Collaborative | Recruiting | Cambridge | Massachusetts | 02139 | United States | |
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| ID | Term |
|---|---|
| D003863 | Depression |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| Non-Heated Yoga |
| Behavioral |
Non-heated yoga described in arm/group description |
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| Weeks 0, 4, 8, and 20 |
| Patient Reported Outcomes Measurement Information System-29 (PROMIS-29) | This measure has seven health domains (physical function, fatigue, pain interference, depressive symptoms, anxiety, social functioning, sleep disturbance). The scale includes four items per domain, each scored from 1 to 5. The scale also includes one question at the end about pain intensity, which is scored from 0 to 10. The possible score for each domain ranges from 4 to 20 and the total possible score for the entire measure ranges from 28 to150. Higher scores indicate poorer outcomes. | Weeks 0, 4, 8, and 20 |
| Ruminative Responses Scale (RRS) | This measure is a 22-item questionnaire, commonly used to assess rumination. Items are scored from 1 to 4, the scale has a possible range of 22 to 88, and higher scores indicate poorer outcomes (i.e. higher rumination). | Weeks 0, 4, 8, and 20 |
| The Five Facet Mindfulness Questionnaire (FFMQ-15) | A self-report instrument that measures mindfulness; derived from factor analytic study of five independent mindfulness questionnaires. The scale contains 39 items, split into five domains (Observing, Describing, Acting with Awareness, Nonjudging, Nonreactivity), with each item being rated from 1 to 5. Some items are reverse coded. Total FFMQ scores range from 39 to 195, with greater scores indicating better outcomes (i.e. greater mindfulness). | Weeks 0, 4, 8, and 20 |
| Breathe Yoga Studio |
| Recruiting |
| Cambridge |
| Massachusetts |
| 02142 |
| United States |
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