Tranexamic Acid in Pediatric Scoliosis Surgery

Effect of ROTEM®-Guided Algorithm for Tranexamic Acid Administration in Pediatric Scoliosis Surgery: a Prospective Randomized Controlled Trial

This study aims to investigate whether intraoperative administration of tranexamic acid based on ROTEM® (Rotational Thromboelastometry), in pediatric patients undergoing scoliosis surgery, results in a difference in intraoperative blood loss when compared to the prophylactic administration of tranexamic acid.

Inclusion Criteria:

• Children undergoing scoliosis surgery under the age of 18

Exclusion Criteria:

• Patients with coagulation disorders
• Patients at an increased risk of thrombosis
• Patients with a history of epilepsy or brain surgery
• Patients with a previous allergic reaction or anaphylaxis history to tranexamic acid
• Severe liver or kidney impairment
• Other cases deemed inappropriate by the researcher