Herbal Pralines - Oral Health

Impact of the Daily Consumption of Herbal Pralines on Parameters of Oral Health in Crew Members of a Naval Ship at Sea - a Randomized Controlled Trial

This randomized, double-blinded, placebo-controlled two-arm, parallel group clinical trial is designed to evaluate the impact of the consumption of two herbal pralines containing 200 mg nitrate on clinical signs of gingival inflammation (Bleeding on probing) without an accompanied professional mechanical plaque removal.

Inclusion Criteria:

• age 18 to 65 years,
• minimum of 20 % of the measure points showing a manifest bleeding after probing,
• no periodontal maintenance therapy within the past 4 months,
• a minimum of 10 remaining natural teeth

Exclusion Criteria:

• history of drug / alcohol abuse,
• systemic intake of antibiotics < 6 months prior to the study period,
• regular use of anti-inflammatory drugs,
• regular use of antibacterial mouthwashes,
• known allergic reactions to any ingredient in the experimental pralines
• mean arterial blood pressure MAD <80mmHg
• known allergies and intolerances to any of the ingredients of the experimental pralines