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The aim of this retrospective observational study is to evaluate the efficacy of antibiotic therapy with dalbavancin in patients presenting with infection on prosthetic devices. The main questions the study aims to answer are:
What is the proportion of patients with early discontinuation of dalbavancin therapy? What are the reasons for early discontinuation of antibiotic treatment? What adverse events do patients report? The study is based on data collected as part of routine care practices.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dalbavancin Injection | Drug | Dalbavancin as long-term suppressive therapy. |
| Measure | Description | Time Frame |
|---|---|---|
| efficacy of suppressive Dalbavancin therapy | Proportion of patients successfully treated with Dalbavancin. The efficacy of suppressive therapy will be defined over a two-year period after initiation of treatment as the combination of the following criteria: Clinical control of infection :
Biological control: o CRP negative (<5mg/l) ; | two-year follow-up after initiation of suppressive therapy with Dalbavancin |
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Inclusion Criteria:
Exclusion Criteria:
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Patients hospitalized for a prosthetic device infection requiring suppressive antibiotic therapy for more than 6 months.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CH Tourcoing | Tourcoing | France |
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| ID | Term |
|---|---|
| D016459 | Prosthesis-Related Infections |
| ID | Term |
|---|---|
| D007239 | Infections |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| C469289 | dalbavancin |
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