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Gynecological cancer is cancer that starts in the female reproductive organs. Pain in gynecological cancer can be caused by an underlying malignancy or surgical procedure as well as chronic pain associated with malignancy and sequelae of the therapy given. Gynecological cancer patients often experience moderate to severe pain and use higher levels of opioids than patients diagnosed with other cancers. More than two thirds of patients with advanced cancer experience severe pain and up to half of these patients report that their pain is not well controlled. This study aims to analyze the effectiveness of electroacupuncture plus standard therapy on pain intensity (VAS score), changes in analgesic dose, and quality of life (QLQ C-30 EORTC score) in patients with gynecological cancer pain compared to standard therapy alone.
This study was conducted using single blinded randomized control clinical trial, design in 58 patients diagnosed with gynecological cancer, aged 18 to 65 years, who experienced cancer pain, with VAS ≥ 4, pain caused by a tumor, before or while undergoing a therapeutic process (radiation therapy, chemotherapy, or post surgery), side effects or due to the toxicity of cancer treatment, willing to take part in this study and sign informed consent who were randomized into 2 groups, namely group I electroacupuncture with standard therapy and group 2 standard therapy, the acupuncture points used were LI4, PC6, ST36, SP6 and LR3, after the acupuncture needle was inserted, the needle was connected to the electrosimulator. The outputs assessed were pain intensity using the VAS, changes in analgesic dose, and quality of life with the EORTC QLQ C-30 questionnaire, which was assessed on the day before starting therapy, the first day, the second day, the third day, the fifth day and the seventh day.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | No Intervention | The Patient are cancer patient that experience cancer pain that only receive analgetic drug treatment according to WHO Stepledder of Pain | |
| Electroacupuncture and standard Therapy | Experimental | The Patient are cancer patient that experience cancer paint that receive analgetic drug treatement according WHO stepledder of pain and receive electroacupuncture |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electroacupuncture | Other | Patient receive analgetic medicine will get experimental procedure with needle insertion that attach to eletrostimulator |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain severity with Visual Analog Scale | Rating scale for measuring pain, where the minimum value is 0 = no pain, and the maximum value is 100 = severe pain. A higher scale means worse outcomes. | Before treatment, After treatment in day 1, day 2, day 3, day 5 and day 7 |
| Measure | Description | Time Frame |
|---|---|---|
| European Organisation for Research and Treatment of Cancer Quality of Life C30 | A Quesionaire for measuring quality of Life | before treatment and 7 day after treatment |
| Analgetic Usage in dosage and frequency |
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Inclusion Criteria:
Female 18 to 65 years old
Gynecocal cancer with pain ≥ 4 acording Visual Analog scale and receive analgetic medicine
The pain cause by
Exclusion Criteria:
Female with gynecology cancer
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| Name | Affiliation | Role |
|---|---|---|
| KEPK FKUI-RSCM | The Ethics Committee of the Faculty of Medicine, University of Indonesia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fatmawati Hospital | Jakarta | DKI Jakarta | 12430 | Indonesia | ||
| Persahabatan Hospital |
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| ID | Term |
|---|---|
| D000072716 | Cancer Pain |
| ID | Term |
|---|---|
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D015671 | Electroacupuncture |
| ID | Term |
|---|---|
| D003131 | Combined Modality Therapy |
| D013812 | Therapeutics |
| D015670 | Acupuncture Therapy |
| D000529 | Complementary Therapies |
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asessor
by assessing drug dose reductions and frequency before and after
| Before treatment, After treatment in day 1, day 2, day 3, day 5 and day 7 |
| Jakarta |
| DKI Jakarta |
| 13230 |
| Indonesia |
| Cipto Mangunkusumo Hospital | Jakarta Pusat | DKI Jakarta | 10430 | Indonesia |
| D004599 |
| Electric Stimulation Therapy |
| D026741 | Physical Therapy Modalities |
| D012046 | Rehabilitation |
| D004561 | Transcutaneous Electric Nerve Stimulation |
| D000698 | Analgesia |
| D000760 | Anesthesia and Analgesia |
| D000758 | Anesthesia |