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Velopharyngeal insufficiency is defined as the inability of the soft palate to isolate the nasopharynx from the oropharynx. It is a frequent sequela in patients with a velopalatine cleft despite anatomical restoration of the soft palate by intravelar veloplasty at 6 months. If rehabilitation by a speech therapist is not successful, a pharyngoplasty can be discussed. In the last ten years, MRI was used in dynamic and static way, to analyzed velopharyngeal muscles, in particular Levator Veli Palatini. MRI could be used to identify the etiology of VPI in those patients, and thus allow personalized rehabilitation and surgical management. The aim of this study is to examine the differences in velopharyngeal motricity as well as velar muscles morphology, positioning, and symmetry of children with repaired cleft palate with different degrees of severity of velopharyngeal insufficiency (VPI), and children with labial cleft (noncleft palate anatomy).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| child with operated isolated labial cleft | Experimental |
| |
| child with isolated operated velopalatal cleft with severe VPI ( IIB//IIM) and normal velum anatomy | Experimental |
| |
| child with isolated operated velopalatal cleft with soft VPI (I/I-II) and abnormal velum anatomy | Experimental |
| |
| child with isolated operated velopalatal cleft with normal anatomy and soft VPI | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| real time MRI | Other | ubjects will be scanned in the supine position using ACHIEVA 3T TX DStream Philips® and a 33 channels head and neck coil. An elastic strap will be fixed to the forehead to limits movement during scan. Headset will be used to cancel the loud MRI noise and to communicate with the subjects |
| Measure | Description | Time Frame |
|---|---|---|
| ratio between the diameter of pharynx at rest and during phonation. | day 1 | |
| closure distance between the velar knee and the posterior pharyngeal wall | day 1 | |
| distance between the velar knee and the posterior pharyngeal wall | day 1 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Cica-Carole GBAGUIDI, MD | Contact | 0322089050 | Gbaguidi.Cica-Carole@chu-amiens.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Amiens-Picardie | Recruiting | Amiens | 80054 | France |
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|
| ID | Term |
|---|---|
| D014681 | Velopharyngeal Insufficiency |
| D002972 | Cleft Palate |
| ID | Term |
|---|---|
| D009056 | Mouth Abnormalities |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D010608 | Pharyngeal Diseases |
| D018640 | Stomatognathic System Abnormalities |
| D010038 | Otorhinolaryngologic Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D007569 | Jaw Abnormalities |
| D007571 | Jaw Diseases |
| D009140 | Musculoskeletal Diseases |
| D019767 | Maxillofacial Abnormalities |
| D019465 | Craniofacial Abnormalities |
| D009139 | Musculoskeletal Abnormalities |
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