The goal of this clinical study is to explore whether preoperative application of 3D reconstruction tool can reduce the occurrence of ischemic complications in the flap and nipple areola complex after surgery.

The 3D reconstruction tool was applied preoperatively to assess the blood supply and volume of participants' breasts and to recommend personalized prosthesis volume. Compared with electrosurgical knife separation，the flap was separated intraoperatively using a combination of cold knife and electrosurgical knife to observe whether there was a difference in the incidence of ischemic complications of participants' nipple areola complex and flap, and whether the use of the 3D tool in the preoperative assessment was effective in reducing the occurrence of postoperative ischemic complications.

Inclusion Criteria:

• Pathologically confirmed diagnosis of breast cancer
• Age: 18 to 70 years old
• No infiltration of the nipple-areola complex and negative histopathology of the nipple basal margins;
• Participants who meet the indications for breast conserving surgery require total mastectomy and reconstruction;

Exclusion Criteria:

• Inability to tolerate surgery or subjective desire not to undergo nipple-sparing mastectomy;
• Participants with clinical or imaging evidence of preoperative involvement of the nipple/areolar region, including Paget's disease, nipple spillage, inflammatory breast cancer, and/or imaging findings suggesting malignant involvement of the nipple or subareolar tissues, according to the 2023 NCCN guideline recommendations, where retaining the NAC fails to yield negative margins;