Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study will be conducted on 28 participants who are survivors of breast cancer and underwent radiotherapy. The purpose of the current study is to investigate the effect of aerobic exercises on quality of life and serum levels of Zinc, Copper and iron in post-menopausal women who received radiotherapy after surviving breast cancer.
Breast cancer (BC) is the most common type of cancer in women globally. Several studies observed changes in the serum blood levels of trace elements in BC. Essential trace elements have relevant functions in a large number of cellular processes, with multiple roles in the correct functioning of metabolic enzymes.
There were previous trials to investigate the effect of exercise on trace elements in different populations as in the elite sportsmen. Some other studies to investigate the effect of exercise on breast cancer survivors for instance stated that physical exercise has effects on psychosocial functioning and health-related quality of life in breast cancer patients and survivors. Also, stated that aerobic exercise is the possible easiest solution to improve quality of life. Lastly, proved that exercise during adjuvant radiotherapy for breast cancer has positive impact on reducing fatigue and improve quality of life . However, there are no previous studies to investigate the effect of exercise on trace elements in BC patients nor identifying the optimal dose or parameters of the exercise. So, this study is an attempt to add to the clinical knowledge in this field as it will be the first one that investigates the effect of aerobic exercise on trace elements in women survived BC.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Aerobic exercise three times a week | Experimental | The participants will receive mild to moderate aerobic exercise for three weeks for 12 sessions. |
|
| No Exercise group | No Intervention | This group will act as a control group. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Aerobic Exercise three time a week | Other | The participants will receive mild to moderate aerobic exercise for three weeks for 12 sessions. |
|
| Measure | Description | Time Frame |
|---|---|---|
| trace elements levels | Blood testing for Fe, Zn, and Cu elements | 2 months |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life questionnaire (EORTC QLQ-C30) | Quality of life will be assessed using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). This instrument includes multiple scales: Global Health Status/Quality of Life, five functional scales (Physical, Role, Emotional, Cognitive, and Social functioning), and several symptom scales/items. Each scale is transformed to a score ranging from 0 to 100. For the Global Health Status/Quality of Life scale and functional scales, higher scores indicate a better level of functioning and quality of life. For the symptom scales/items, higher scores indicate a greater level of symptoms or problems (worse outcome). |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tarek Hussein | Cairo | Cairo Governorate | 11931 | Egypt |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
Not provided
Not provided
Aerobic exercises and no intervention
Not provided
Not provided
Not provided
| 2 months |
| D017437 |
| Skin and Connective Tissue Diseases |