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| Name | Class |
|---|---|
| First Affiliated Hospital, Sun Yat-Sen University | OTHER |
| Third Affiliated Hospital, Sun Yat-Sen University | OTHER |
| Affiliated Hospital of Guangdong Medical University | OTHER |
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This study is a multicenter cohort study including patients diagnosed with aortic valve disease during hospitalization, including aortic insufficiency and aortic valve stenosis. The primary outcome of the study was all-cause death, and the secondary outcome was cardiovascular events. Through follow-up observation, the prognostic risk factors of patients with aortic disease were evaluated, and a prognostic model was constructed to guide clinical decision-making.
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| Measure | Description | Time Frame |
|---|---|---|
| all-cause mortality | death caused by any cause | from baseline to death or end of follow-up |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiovascular death | Death caused by cardiac causes | from baseline to death or end of follow-up |
| Aortic valve replacement | Transcatheter aortic valve replacement or surgical aortic valve replacement |
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Inclusion Criteria:
Exclusion Criteria:
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The participant included in this study were patients with aortic valve disease diagnosed during hospitalization, and these patients were followed up for a long time after discharge.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| xiaodong zhuang, PhD | Contact | +86 13760755035 | zhuangxd3@mail.sysu.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| xiaodong zhuang, PhD | First Affiliated Hospital, Sun Yat-Sen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| First Affiliated Hospital, Sun Yat-Sen University | Recruiting | Guangzhou | Guangdong | 510000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41789337 | Derived | Cai X, Hu D, Yan B, Chen J, Li W, Lin Y, Lin R, Ye J, Su J, Tong S, Huang X, Xie B, Zhuang X, Chen J, Li J. Evaluation of EuroSCORE II to Determine the Prognosis of Patients With Moderate-To-Severe Aortic Stenosis: A Long-Term Retrospective Study. Rev Cardiovasc Med. 2026 Feb 4;27(2):42757. doi: 10.31083/RCM42757. eCollection 2026 Feb. | |
| 41076530 |
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| ID | Term |
|---|---|
| D000082862 | Aortic Valve Disease |
| D001024 | Aortic Valve Stenosis |
| D001022 | Aortic Valve Insufficiency |
| ID | Term |
|---|---|
| D006349 | Heart Valve Diseases |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014694 | Ventricular Outflow Obstruction |
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| Second Affiliated Hospital of Shantou University Medical College |
| OTHER |
| Eighth Affiliated Hospital, Sun Yat-sen University | OTHER |
| Zhongshan People's Hospital, Guangdong, China | OTHER |
| Jieyang People's Hospital | OTHER |
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| from baseline to aortic valve replacement |
| Third Affiliated Hospital, Sun Yat-Sun University | Recruiting | Guangzhou | Guangdong | 510000 | China |
|
| Jieyang People's Hospital | Recruiting | Jieyang | Guangdong | 522000 | China |
|
| Second Affiliated Hospital of Shantou University Medical College | Recruiting | Shantou | Guangdong | 515041 | China |
|
| Eighth Affiliated Hospital, Sun Yat-Sen University | Recruiting | Shenzhen | Guangdong | 518000 | China |
|
| Affiliated Hospital of Guangdong Medical University | Recruiting | Zhanjiang | Guangdong | 524001 | China |
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| Zhongshan People's Hospital | Recruiting | Zhongshan | Guangdong | 528400 | China |
|
| Guo Z, Xiong Z, Zhang W, Chen G, Xie M, Zhou Z, Zhang S, Liu M, Li J, Liao X, Zhuang X. Association between cholesterol, high-density lipoprotein, and glucose index and risks of cardiovascular and all-cause mortality in patients with calcific aortic valve stenosis: the ARISTOTLE cohort study. Cardiovasc Diabetol. 2025 Oct 11;24(1):393. doi: 10.1186/s12933-025-02906-2. |
| 39895526 | Derived | Li B, Zhang S, Xu C, Huang M, Xiong Z, Hui Z, Liao X, Li J, Chen J, Zhuang X. Association Between the Malnutrition Status and All-Cause Mortality in Patients With Moderate and Severe Aortic Stenosis: A Prospective Cohort Study. J Am Heart Assoc. 2025 Feb 4;14(3):e037086. doi: 10.1161/JAHA.124.037086. Epub 2025 Feb 3. |
| 39881345 | Derived | Guo Z, Xiong Z, He L, Zhang S, Xu X, Chen G, Xie M, Zhang W, Hui Z, Li J, Liao X, Zhuang X. Association between triglyceride-glucose-body mass index and risk of aortic stenosis progression in patients with non-severe aortic stenosis: a retrospective cohort study. Cardiovasc Diabetol. 2025 Jan 29;24(1):46. doi: 10.1186/s12933-025-02579-x. |