Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
To detect short-term impacts of successful balloon mitral valvuloplasty on right ventricular function
In patients with mitral valve stenosis, right ventricular failure may develop either by the rheumatic process directly or through hemodynamic alterations resulting from pulmonary vascular changes.
Right ventricular (RV) function plays an important role in development of clinical symptoms and prognosis in patients with mitral stenosis (MS).This is primarily affected by hemodynamic effects on RV due to pulmonary hypertension(PH).
In the last two decades, Percutaneous Transluminal Mitral Commissurotomy (PTMC) has become the treatment of choice for patients with symptomatic rheumatic MS . Using this method,Mitral Valve Area (MVA) can be increased, which can improve the hemodynamic and clinical features of patients with MS .
RV functional assessment is difficult and not done routinely because of its complex anatomy and high load dependence.
Different modalitis are used to assess RV function as Tissue Doppler and two-dimensional (2D) speckle tracking method has been used to quantify strain for assessment Myocardial strain is a measure of tissue deformation, which is expressed as a percentage change.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| To compare RV function before and after PTMC | echocardiogram | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| To measure the right side pressure changes invasively before and after PTMC | Right sided heart catheterization | 1 year |
| To compare the effect of PTMC on RV function in patient with AF and sinus rythm |
Not provided
Inclusion Criteria:
Patient with isolated mitral stenosis (except those with mild mitral regurgitation and are candidate for PTMC by 2D Echo evaluation).
Exclusion Criteria:
Not provided
Not provided
Not provided
Patients with severe mitral stenosis,not impairment left ventricular function
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yassmin Zakaria Basheir | Contact | 01115429471 | Yass.min97@yahoo.com | |
| Hamdy Shams-eddin Mohammad, Professor | Contact | 01065601161 | ashams98@yahoo.com |
Not provided
Not provided
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24814111 | Background | Kumar V, Jose VJ, Pati PK, Jose J. Assessment of right ventricular strain and strain rate in patients with severe mitral stenosis before and after balloon mitral valvuloplasty. Indian Heart J. 2014 Mar-Apr;66(2):176-82. doi: 10.1016/j.ihj.2014.02.012. Epub 2014 Mar 1. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D008946 | Mitral Valve Stenosis |
| ID | Term |
|---|---|
| D006349 | Heart Valve Diseases |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
| 1year |