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A cost-utility analysis based on an earlier published RCT comparing surgery with volar locking plate to non-operative treatment for the elderly with a displaced distal radius fracture.
Study design: A cost-utility analysis of a patient population included in a previous published randomized controlled trial.
Patient population:140 patients 70 years of age or older with a displaced distal radius fracture that met the inclusion and no exclusion criteria at Danderyd Hospital or Södersjukhuset Hospital were randomized to volar locking plate or non-operative treatment with a cast.
Primary outcome: Incremental cost-effectiveness ratio (ICER) at 1 and 3 years.
Data collection: Prospectively collected clinical data is available for 4, 12, weeks, 1 and 3 years. Costs will be analysed regarding surgical equipment, inpatient stay, surgical time. Prescriptions of analgesics and antibiotics as well as inpatient and outpatient consumption over a three years period after the injury will be retrieved from the Swedish National Board of Health and Welfare.The life expectancy adjusted life years (QALYs) is calculated from prospectively collected results from EQ-5D.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Volar Locking Plate | Experimental | Surgery with a Volar Locking Plate due to displaced distal radius fracture |
|
| Non-operative treatment group | Experimental | Patients allocated to non-operative treatment received a plaster cast for 4-5 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Volar Locking Plate | Procedure | Surgery |
| |
| Plaster Cast |
| Measure | Description | Time Frame |
|---|---|---|
| Incremental Cost-Effectiveness Ratio (ICER) at 1 year. | difference in cost divided by difference in quality of life | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Absolute cost difference | difference in cost between treatments | 1 and 3 years |
| ICER at 3 years | difference in cost divided by difference in quality of life |
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Inclusion Criteria
Exclusion Criteria
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| Name | Affiliation | Role |
|---|---|---|
| Olof Sköldenberg, professor | Karolinska Institutet | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Division ot Ortopeadics | Stockholm | Sweden |
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Parallell study arms with the intervention volar locking plate and control treatment forearm cast. We investigate the difference in health cost between the two groups.
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| Procedure |
Non-operative treatment with a plaster cast |
|
| 3 years |
| ID | Term |
|---|---|
| D011885 | Radius Fractures |
| D000092503 | Wrist Fractures |
| D014954 | Wrist Injuries |
| D011183 | Postoperative Complications |
| D010342 | Patient Acceptance of Health Care |
| ID | Term |
|---|---|
| D005543 | Forearm Injuries |
| D001134 | Arm Injuries |
| D014947 | Wounds and Injuries |
| D050723 | Fractures, Bone |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000074822 | Treatment Adherence and Compliance |
| D015438 | Health Behavior |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D002370 | Casts, Surgical |
| ID | Term |
|---|---|
| D016267 | External Fixators |
| D009984 | Orthopedic Fixation Devices |
| D009983 | Orthopedic Equipment |
| D013523 | Surgical Equipment |
| D004864 | Equipment and Supplies |
| D053831 | Surgical Fixation Devices |
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