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The CHANNELED-Registry is a multicenter retrospective study to (1) systematically assess the mechanism and origin of ventricular tachycardia in patients with end-stage heart failure carrying an left ventricular assist device (LVAD) and (2) to evaluate procedural parameters and outcome of ventricular tachycardia ablation in this special subset of patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| LVAD patients | Patients with end-stage heart failure with an LVAD implanted undergoing VT ablation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ablation | Other | VT ablation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mechanism of ventricular tachycardia in LVAD patients (descriptive name of scale) | Assessment of the mechanism of VT in LVAD patients (e.g LVAD cannula related vs. related to substrate of underlying heart disease) | 12 month |
| Number of patients with ventricular tachycardia recurrence in device interrogation (physiological parameter) | Assessment of VT recurrence after ablation: Device interrogation and readout of ICD Holter | 12 month |
| Mortality (physiological parameter) | Assessment of mortality after VT ablation. | 12 month |
| Heart failure Hospitalization (physiological parameter) | Assessment of Hospitalization for worsening of Heart Failure after VT ablation. | 12 month |
| Measure | Description | Time Frame |
|---|---|---|
| Procedure duration (From groin puncture to sheath removal in minutes) | Evaluation of the duration of VT ablation procedures in LVAD patients | 12 month |
| Fluoroscopy time (minutes) | Evaluation of the fluroscopy use (in minutes) |
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Inclusion Criteria:
Exclusion Criteria:
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All patients with end-stage heart failure and an implanted LVAD which underwent ablation of ventricular tachycardia will be included in this retrospective observational study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jakob Lüker, MD | Contact | +49 221 478 82851 | jakob.lueker@uk-koeln.de | |
| Jan-Hendrik van den Bruck, MD | Contact | +49 221 478 84895 | jan-hendrik.van-den-bruck@uk-koeln.de |
| Name | Affiliation | Role |
|---|---|---|
| Jakob Lüker, MD | Heart Center University of Cologne | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40101155 | Derived | van den Bruck JH, Hohendanner F, Heil E, Albert K, Duncker D, Estner H, Deneke T, Parwani A, Potapov E, Seuthe K, Wormann J, Sultan A, Schipper JH, Eckardt L, Doldi F, Lugenbiel P, Servatius H, Thalmann G, Reichlin T, Khalaph M, Guckel D, Sommer P, Steven D, Luker J. Characterization of ventricular tachycardia ablation in end-stage heart failure patients with left ventricular assist device (CHANNELED registry). Europace. 2025 Mar 28;27(4):euaf054. doi: 10.1093/europace/euaf054. |
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| ID | Term |
|---|---|
| D017180 | Tachycardia, Ventricular |
| ID | Term |
|---|---|
| D013610 | Tachycardia |
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| 12 month |
| Radiofrequency energy used for ablation (in watts; e.g. 40 Watts) | Evaluation of the maximum RF-energy used for ablation | 12 month |
| Number of patients suffering from intraprocedural complication (physiological parameter, e.g. hematoma) | Evaluation of intraprocedural complications of VT ablation | 12 month |
| D000075224 |
| Cardiac Conduction System Disease |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |