Furcation involvement represents a challenge for treatment to many periodontists due to many factors including access, morphology, and variations of anatomical features of the furcation area. Furcation involvement treatment includes non-surgical periodontal therapy, resective surgery and regenerative surgery, regenerative therapy utilizing different graft materials and membranes is of high cost and research for new materials that can be cost-effective and available for all patients is continuing, propolis have been shown to be cost-effective therapy for bone and wound healing.

Propolis is a natural resinous product of the bee workers collected from trees to use it to stick their hives and form a coat to protect their hives from all sources of bacteria and invasions. Propolis is composed of more than 300 compounds, the most important of them are flavonoids like CAPE (caffeic acid phenyl ester). Propolis have shown anti-inflammatory, anti-oxidant, anti-bacterial, anti-fungal, anti-viral and more importantly regenerative effect and bone formation capabilities.

Inclusion Criteria:

• Inclusion criteria:

  1. Lower molars with class II furcation defects.
  2. Full mouth plaque score (FMPS )<20% at baseline.
  3. Full mouth bleeding score (FMBS )<10% at baseline.
  4. Systemically healthy.
  5. Cooperative patients.

Exclusion Criteria:

• Exclusion criteria:

  1. Smokers.
  2. Pregnancy and lactation.
  3. Stage 4 Grade C periodontitis.

one arm (10 participents)

Inclusion criteria:

1. Lower molars with class II furcation defects.
2. Full mouth plaque score (FMPS )<20% at baseline.
3. Full mouth bleeding score (FMBS )<10% at baseline.
4. Systemically healthy.
5. Cooperative patients.

Exclusion criteria:

1. Smokers.
2. Pregnancy and lactation.
3. Stage 4 Grade C periodontitis.