This randomized controlled trial was designed to examine the effect of hand massage on the level of fatigue in patients receiving BT therapy. Randomized controlled trial was conducted in the radioterapi outpatient clinic of university hospital located in a large city in Turkey. When 12 patients were included in each group, it was determined that the power was 90% at the 5% Type I error level, and a total of 24 women with gynecological cancer were included in the study. The primary outcome of this study was the mean difference in fatigue scores between the groups following the three brachtherapy cycles hand intervention. Patient Information Form and Brief Fatigue Inventory (BFI) used. This study predicted that hand massage applied in each session, starting from the first session of brachytherapy application, would reduce the level of fatigue in women.

Therefore, this study aimed to compare the effects of hand massage intervention the level of fatigue in patients receiving BT therapy. . This randomized clinical trial was conducted.

Inclusion Criteria:

• 18 years and over,
• underwent BT regularly
• Patients who volunteered to participate in the study

Exclusion Criteria:

• Having skin problems
• with metastases,
• have bleeding or coagulation disorders,
• using complementary integrated therapy during the study,
• Having edema or wound in the hand area,
• not wanting to get a massage
• Patients receiving general anesthesia during the procedure

The study was conducted in women with gynecological cancer