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| Name | Class |
|---|---|
| Center of Endourology "Endocenter" | OTHER |
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The study attempts to quantify the relative risks for mortality, anastomotic leakage and other early and late postoperative complications, recurrence rate, cancer-specific survival, recurrence-free survival after colorectal surgery for patients with colorectal cancer depending on the localization of the tumor.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with right-sided colon cancer | Tumors located anywhere from the cecum to the proximal transverse colon. |
| |
| Patients with left-sided colon cancer | Tumors located anywhere from the distal transverse colon to the rectosigmoid junction |
| |
| Patients with rectal cancer | Tumors located in rectosigmoid junction and in the rectum with/without the external sphincter or the levator muscles invasion |
| |
| Patients with right- and left-sided colon cancer (primary multiple cancer) | Patients with primary multiple cancer tumors |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Right hemicolectomy | Procedure | Resection of the caecum and ascending colon is appropriate for patients with tumors located anywhere from caecum to the transverse colon |
|
| Measure | Description | Time Frame |
|---|---|---|
| Anastomotic leakage rate | Anastomotic leakage rate after colorectal resection. AL is confirmed by one or more of the following conditions:
| 3 months after surgery |
| Mortality rate | the overall mortality after colorectal cancer surgery | 3 years after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| 30-day complication rate | The number of patients with complications after colorectal resection. All complications will be assessed according to the Clavien-Dindo classification. It consists of 7 grades (I, II, IIIa, IIIb, IVa, IVb and V). Grade I - Any deviation from the normal postoperative course without the need for treatment. Grade II - Requiring pharmacological treatment with drugs other than such allowed for grade I complications. Grade III - Requiring surgical, endoscopic or radiological intervention
|
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Inclusion Criteria:
Exclusion Criteria:
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An unselected, consecutive regionwide cohort during 3 years, with a 3-year follow-up
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tatiana N Garmanova, PhD | Contact | +79773429249 | tatianagarmanova@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Mikhail A Agapov, PhD | Baltic Federal University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Baltic Federal University | Recruiting | Kaliningrad | Kaliningrad Oblast | 236041 | Russia |
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| Left hemicolectomy | Procedure | Resection of the sigmoid colon is appropriate for patients with tumors located anywhere from the distal transverse colon to the rectosigmoid junction. |
|
| Sigmoid colon resection | Procedure | Resection of the sigmoid colon is appropriate for patients with tumors located in the sigmoid colon |
|
| Anterior resection of the rectum | Procedure | AR is appropriate for tumors located in rectosigmoid junction and in the proximal rectum |
|
| Low anterior resection of the rectum | Procedure | LAR is appropriate for tumors located in the middle and low rectum |
|
| Abdominoperineal resection | Procedure | APR is appropriate for distal rectal cancers that invade the external sphincter or the levator muscles |
|
| Total Colectomy | Procedure | Total abdominal colectomy may be indicated for patients with primary multiple cancer tumors |
|
| 30 days after surgery |
| Recurrence rate | All cases of colorectal cancer recurrence | 3 years after surgery |
| Cancer-specific survival | The number of patients survived within 3 years after the diagnosis | 3 years after surgery |
| Recurrence-free survival | The number of patients without cancer recurrence within 3 years after surgery | 3 years after surgery |
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D003110 | Colonic Neoplasms |
| D012004 | Rectal Neoplasms |
| D057868 | Anastomotic Leak |
| D011183 | Postoperative Complications |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D000078542 | Proctectomy |
| ID | Term |
|---|---|
| D000099090 | Surgical Procedures, Colorectal |
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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