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| Name | Class |
|---|---|
| University of Saskatchewan | OTHER |
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The goal of this clinical trial is to determine the postprandial glycemic response of the two starches in humans. Participants will be asked to consume 2 test foods on 2 separate occasions and provide blood glucose samples over 120 minutes postprandial.
Enrolled participants who are generally healthy and free of major chronic conditions will be randomized to receive either Commercial Native Starch or Extrusion Processed Starch first and then will be crossed over to receive the opposite Intervention. The study will consist of two clinical test visits of 120 minutes separated by a washout period of at least 24 hours.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Native Starch, then Processed Starch | Experimental | Participants will first receive the Commercial Native Starch in a fasting state in one clinical visit. After a washout of >24 hours, the participants will then receive the Extrusion Processed Starch in a fasting state in one clinical visit. |
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| Processed Starch, then Native Starch | Experimental | Participants will first receive the Extrusion Processed Starch in a fasting state in one clinical visit. After a washout of >24 hours, the participants then will receive the Commercial Native Starch in a fasting state in one clinical visit. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Commercial native starch without processing | Other | A food-grade commercial native starch without processing that has been rehydrated into a pudding for oral consumption. |
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| Measure | Description | Time Frame |
|---|---|---|
| Postprandial Glycemia | Incremental area under the curve for blood glucose over 120 minutes. | -5 to 120 minutes after intervention administration |
| Measure | Description | Time Frame |
|---|---|---|
| Incremental Blood Glucose | Change in blood glucose from baseline at each time point | 0, 15, 30, 45, 60, 90, and 120 minutes after intervention administration |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Thomas MS Wolever, MD, PhD, DM (Oxon) | INQUIS Clinical Research | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| INQUIS Clinical Research Ltd. | Toronto | Ontario | M5C 2N8 | Canada |
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| Modified starch with extrusion processing | Other | A food-grade modified starch with extrusion processing that has been rehydrated into a pudding for oral consumption. |
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