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| Name | Class |
|---|---|
| Cooperative University of Colombia | OTHER |
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Background: Acute cholecystitis is a frequent cause of visits to the emergency ward. The complications of delays in attention and surgical therapy are substantial and should be considered to prevent them timely.
Objective: The study aims to evaluate the assistance provided to patients for cholecystitis in Villavicencio hospitals.
Methodology: A retrospective cross-sectional trial will be performed. The source of information will be the surgical database of hospitals at Villavicencio from 2019 to 2022. The records selected will be exported to an Excel spreadsheet for debugging and analysis. The central distribution and dispersion of numerical variables will be analyzed, as frequency and proportion of categorical variables with the software Prism 10.01.1 for Mac iOS. Chi-square and U-Mann & Whitney tests will compare variables according to the data type. A p<0.05 will be defined as statistically significant.
Expected results: the researchers hope to define the frequency of hospital discharges due to acute cholecystitis, the type of procedure performed, complications, and outcomes.
Conclusions: The research is feasible because the necessary information is available for evaluation, and it is helpful for the institutions and the region.
Biliary diseases are some leading causes of admission to emergency wards. Cholelithiasis and acute cholecystitis are prevalent in the Orinoquia region. Young and female populations are predominantly affected. Complications are prone to delayed definitive surgical therapy, which increases costs and the use of resources. Guidelines recommend early surgery during hospitalization for the first episode to minimize difficulties. There are limitations in the available technology recommended for treatment, especially in institutions dedicated to vulnerable populations. Laparoscopic cholecystectomy is the primary goal in cases required for gall bladder removal. Although the technology and trained personnel are available in local institutions, open procedures are still performed primarily, and restrictions are due to insurance coverage after more than 30 years of disseminating laparoscopic cholecystectomy worldwide.
It is necessary to know the prevalence of the disease and the therapy provided in general hospitals from the region to analyze associated factors with undesired results.
Determining the characteristics of patients admitted to hospitals by biliary pathology will provide essential information on the severity, care provided, definitive treatment, opportunity, and outcomes. Such an analysis will give knowledge to prioritize policies and resources, upgrade clinical practice guidelines, and improve early and long-term results.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Number of patients with early therapy | Patients with early surgery (<72 hours of admission). |
| |
| Number of patients with subacute therapy | Patients with surgery for three days or more. |
| |
| Number of patients with late therapy | Patients with surgery beyond ten days. |
| |
| Number of patients with no therapy | Patients discharged with no surgical therapy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cholecystectomy | Procedure | Early or late surgery, ambulatory, emergency, or differed. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | Number of patients deceased due to the biliary disease, complications, or other conditions. | 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| Hospital length of stay | Number of days before discharge. | 28 days |
| Need of ICU | Patients admitted to ICU under any circumstance. | 28 days |
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Inclusion Criteria:
Exclusion Criteria:
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The trial participants are those admitted requesting emergency, hospital, ambulatory, or ICU attention for biliary pathology during the study period, according to the admission registers.
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| Name | Affiliation | Role |
|---|---|---|
| Norton Perez, MD | Cooperative University of Colombia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinica Primavera | Villavicencio | Meta Department | 50001 | Colombia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Result | Serna JC, Patiño S, Buriticá M, Osorio E, Morales CH, Toro JP. Incidencia de lesión de vías biliares en un hospital universitario: análisis de más de 1.600 colecistectomías laparoscópicas. Rev Colomb Cir. 2019;34(1):45-54. | ||
| Result | Sanchez Beorlegui J, Monsalve Laguna E, Aspiroz Sancho A, Moreno de Marcos N. Colecistectomía laparoscópica en octogenarios. Rev Colomb Cir. 2008;23(3):136-45. | ||
| Result | Castro F, Galindo J, Bejarano M. Complicaciones de colecistitis aguda en pacientes operados de urgencia. Rev Colomb Cir. 2008;23(1):15-21. | ||
| Result | Domínguez LC, Herrera WE, Rivera AM, Bermúdez CE. Colecistectomía de urgencia por laparoscopia por colecistitis aguda en adultos mayores. Rev Colomb Cir. 2011;26:93-100. | ||
| Result | Díaz S, Correa MJ, Giraldo LM, Ríos DC, Solórzano F, Wolff JD, et al. Experiencia en colecistectomía por laparoscopia en la Clínica Universitaria CES. Rev Colomb Cir. 2012;27(4):275-80. | ||
| Result | Gaitán JA, Martínez VM. Enfermedad litiásica biliar, experiencia en una clínica de cuarto nivel, 2005-2011. Rev Colomb Cir. 2014;29(3):188-96. | ||
| Result | Salinas C, López CA, Ramírez A, Torres R, Mendoza MC, Cuesta DP, et al. Colecistectomía por laparoscopia en colecistitis subaguda: análisis retrospectivo de pacientes en un hospital universitario. Rev Colomb Cir. 2018;33(2):154-61. |
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According to the decision of the ethical committee, the database might be stored in the repository of the university.
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| ID | Term |
|---|---|
| D001660 | Biliary Tract Diseases |
| D041881 | Cholecystitis, Acute |
| D005705 | Gallbladder Diseases |
| D041761 | Cholecystolithiasis |
| ID | Term |
|---|---|
| D004066 | Digestive System Diseases |
| D002764 | Cholecystitis |
| D002769 | Cholelithiasis |
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| ID | Term |
|---|---|
| D002763 | Cholecystectomy |
| ID | Term |
|---|---|
| D001662 | Biliary Tract Surgical Procedures |
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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| ICU length of stay | Number of days hospitalized in ICU | 28 days |
| Surgical site infection | Number of patients with infections associated with the procedure (superficial, deep, organ/space) | 28 days |
| Need of mechanical ventilation | Number of patients needing mechanical ventilation | 28 days |
| Complicated presentation | Number of patients with complications of the disease previous or during hospitalization, but not related to the surgical procedure | 28 days |
| Surgical complications | Number of patients with complications related to the surgical procedure | 28 days |
| Result | Ángel-González MS, Díaz-Quintero CA, Aristizábal-Arjona F, Turizo-Agamez Á, Molina-Céspedes I, Velásquez-Martínez MA, et al. Controversias en el manejo de la colecistitis aguda tardía. Rev Colomb Cir. 2019;34(4):364-71. |
| Result | Arroyave Y, Torres F, Sarzosa F, Díaz J, Arroyave Y, Torres F, et al. ¿Es más difícil la colecistectomía laparoscópica después de una colangiopancreatografía retrógrada endoscópica? Experiencia en un hospital de tercer nivel. Rev Colomb Cir. 2020;35(3):436-48. |
| Result | Bustos-Guerrero AM, Guerrero-Macías SI, Manrique-Hernández EF, Gomez-Rincón GA. Severidad de la colecistitis aguda en tiempos de COVID-19: ¿mito o realidad? Rev Colomb Cir. 2022;37(2):206-13. |
| Result | Vargas Rodríguez LJ, Agudelo Sanabria MB, Lizcano Contreras RA, Martínez Balaguera YM, Velandia Bustcara EL, Sánchez Hernández SJ, et al. Factores asociados con la conversión de la colecistectomía laparoscópica a colecistectomía abierta. Rev Colomb Gastroenterol. 2017;32(1):20-3. |
| Result | Yurgaky-Sarmiento J, Otero-Regino W, Gómez-Zuleta M, Yurgaky-Sarmiento J, Otero-Regino W, Gómez-Zuleta M. Elevación de las aminotransferasas: una nueva herramienta para el diagnóstico de coledocolitiasis. Un estudio de casos y controles. Rev Colomb Gastroenterol. 2020;35(3):319-28. |
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