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Epilepsy is a chronic disease triggered by increased impulsiveness of nerve cells in the brain and may require a lifelong treatment. Epilepsy is confirmed by two or more unprovoked seizures in more than 24 hours. Febrile Convulsion is another type of seizure occurring due to fever over 38 °C without a history of convulsion, CNS infection, electrolyte imbalance, metabolic disorder, intoxication, and trauma. Unlike epileptic seizures, there are non-epileptic seizures such as Breath Holding Spells that affect children's behaviors and often look like epileptic seizures.
QT parameters elongation show the danger of dysrhythmia and unexpected sicknesses such as cardiomyopathy, mitral valve prolapse, ischemic coronary illness, and kidney disorders.
Many investigators have reported changes in QT parameters in various diseases such as diabetes mellitus, celiac disease, thalassemia , epilepsy ,Breath holding spells and febrile seizure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Drug Resistant Epilepsy | Seizures Not Respond to two lines of Anti epileptic Medications |
| |
| Drug Responsive Epilepsy | Seizures Respond to one or two lines of Anti epileptic Medications |
| |
| Febrile Seizures | type of seizure occurring due to fever over 38 °C without a history of convulsion |
| |
| Breath Holding Spells | children's behaviors look like epileptic seizures due to crying up to a minute followed by losing consciousness |
| |
| Control | Healthy Children free from any convulsion |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ECG | Device | ECG with special comment on QT interval. QT interval was measured as the distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG. |
| Measure | Description | Time Frame |
|---|---|---|
| QT interval | Distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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children with drug resistant epilepsy , responsive epilepsy , febrile seizures and breath holding spells with age of 1 year to 12 years
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Amany K El Zanaty, resident | Contact | 01000465897 | amanykhalaf@med.sohag.edu.eg | |
| Mohamed M Fawaz, professor | Contact |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sohag university Hospital | Sohag | Sohag | Egypt |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jul 7, 2025 | |
| Reset | Jul 23, 2025 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jul 7, 2025 | Jul 23, 2025 |
| ID | Term |
|---|---|
| D012640 | Seizures |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D004562 | Electrocardiography |
| ID | Term |
|---|---|
| D006334 | Heart Function Tests |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| D004568 | Electrodiagnosis |