Biomarkers and Risk Factors for Perioperative Neurocognitive Dysfunction in Elderly Patients

Biomarkers and Risk Factors for Perioperative Neurocognitive Disorders in Elderly Non-neurosurgical Patients

Basic information and biological samples of patients were collected preoperatively and intraoperatively, and patients were divided into case and control groups by cognitive function assessment postoperatively, and risk factors and biomarkers of perioperative cognitive dysfunction were derived by analyzing and statistically processing basic information and biological samples.

Inclusion Criteria:

• Age more than or equal to 65 years old
• ASA classification Ⅰ~Ⅲ grade

Exclusion Criteria:

• History of previous Craniocerebral surgery or Craniocerebral trauma
• Inability to successfully complete preoperative psychological function tests
• Those who are severely deaf, speech impaired and otherwise unable to communicate.