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This is a retrospective study looking at patients who received a nerve block for surgery and assessing pain after the nerve block resolves, with or without an educational intervention, over two periods of time.
Regional anesthesia (RA) is a vital tool that can serve as the primary anesthetic or as part of a multimodal perioperative pain regimen. RA is strongly associated with decreased acute and persistent pain and opioid consumption postoperatively. However, some patients experience an acute worsening of pain into the severe range around the time of RA resolution, also known as "rebound pain" (RP). The incidence of RP has been reported as high as 40-50% after a single shot nerve block for patients undergoing ambulatory surgery.
This retrospective study aims to look at patients who received a nerve block for surgery and assessing pain after the nerve block resolves in the presence and absence of certain interventions, such as a multidisciplinary educational intervention.
The investigators will assess patients who received a primary total knee arthroplasty who received a single shot adductor canal nerve block, received pericapsular injection by the surgeon, and had a length of stay > 16 hours.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| TKA with nerve block no intervention | Patients who received a single shot adductor canal nerve block prior to total knee arthroplasty surgery January 2017-June 2018 | ||
| TKA with nerve block with intervention | Patients who received a single shot adductor canal nerve block prior to total knee arthroplasty surgery during March 2019-March 2020, and received an educational intervention |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Educational intervention | Other | Multidisciplinary educational intervention was performed by orthopedic, anesthesia, and nursing team. This included a discussion of the patient's pain plan and a patient visit. |
| Measure | Description | Time Frame |
|---|---|---|
| Difference in maximum pain score, 0-10; (0 = no pain, 10 = worst pain) | Difference in maximum pain score, numerical pain rating scale 0-10, 6-24 hours after nerve block between the two cohorts | 6-24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Average pain score 0-10; (0 = no pain, 10 = worst pain) | Difference in area under the curve of pain scores, numerical pain rating scale 0-10, 6-24 hours after nerve block between the two cohorts (educational intervention and non-educational intervention time periods) | 6-24 hours |
| Difference in incidence of rebound pain |
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Inclusion Criteria:
Exclusion Criteria:
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Using the Mass General Brigham Enterprise Data Warehouse, electronic health record data will be retrieved: adult patients, 18 years of age or older, who received a primary total knee arthroplasty, an adductor canal nerve block, pericapsular injection, and admitted to stay overnight (>16 hours post nerve block).
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| Name | Affiliation | Role |
|---|---|---|
| Yun-Yun K Chen, MD | Brigham and Women's Hospital | Principal Investigator |
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| ID | Term |
|---|---|
| D059787 | Acute Pain |
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D018479 | Early Intervention, Educational |
| ID | Term |
|---|---|
| D002662 | Child Health Services |
| D003153 | Community Health Services |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |
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Difference in incidence pain score ≥ 7 between 6-24 hours post nerve block between the two cohorts |
| 6-24 hours |
| Comparison of evening opioids given | Comparison of if evening opioids were or were not given (yes/no) between the two cohorts | 6-24 hours |
| Difference in total opioids given | Difference in total opioids given (mEq of morphine) between the two cohorts | 6-24 hours |
| Difference in length of stay | Difference in length of stay (days) between the two cohorts | 0-2 years |
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
| D011314 | Preventive Health Services |