Ketamine Effects as Preemptive Analgesia | NCT06040060 | Trialant

Ketamine Effects as Preemptive Analgesia | NCT06040060 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Preemptive Ketamine	Active Comparator	Preemptive administration of Ketamine 0.5 mg/kgBB intravenously, given 10 minutes prior to incision	Drug: Ketamine
Placebo	Placebo Comparator	Placebo administration of 10 mL NaCl 0,9% intravenously, given 10 minutes prior to incision	Other: Placebo

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Ketamine	Drug	The intervention was prepared by the research team (anesthesia resident) in the form of ketamine which had been diluted to a dosage of 10 mg/cc, taken according to the required dose based on actual body weight then diluted with 0.9% NaCl to 10 cc. Then the two solutions were given to researchers without knowing the contents of the drugs that had been prepared by the resident who assisted in this research.

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Duration of postoperative analgesia	Time interval from completion of hysterectomy until additional analgesic is needed, namely fentanyl 25 µg via PCA	24 hours post operative
Total need for post-operative analgesic rescue	The total amount of rescue analgetic required by research subjects, during the 24 hours after surgery, was given via PCA	24 hours post operative

Contacts/Locations Module

Overall Officials

Name	Affiliation	Role
Iwan Fuadi, MD	Faculty of Medicine Universitas Padjadjaran Bandung	Study Director
Ardi Zulfariansyah, MD	Faculty of Medicine Universitas Padjadjaran Bandung	Study Director
Jacklin E Mokoginta, MD	Faculty of Medicine Universitas Padjadjaran Bandung	Principal Investigator

Condition Browse Module

Intervention Browse Module