Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Independence Blue Cross | OTHER |
Not provided
Not provided
The goal of this clinical trial is to compare a texting platform to usual care for managing recurrent urinary tract infections (UTI).
The main question it aims to answer is:
• can a texting platform that integrates symptom triage and prevention education reduce the rate of unnecessary antibiotics for recurrent UTIs as compared to usual care?
Participants enrolled onto the texting platform will:
• receive evidence-based clinical guidance for the management of symptoms of UTI and receive educational videos on how to prevent UTIs. An important secondary outcome is to determine if the texting platform improves self-efficacy for the management of recurrent UTI.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Electronic health record (EHR)-integrated texting platform | Experimental | Patients will be enrolled into a texting platform for the management of recurrent UTI. |
|
| Usual care | Active Comparator | Patients will receive usual care through their providers. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EHR-integrated texting platform (Urotrust) | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| Rate of unnecessary antibiotics | Antibiotics prescribed for patients when 1) urine culture is negative and/or urine microscopy has pyuria < 10 WBC/HPF, 2) asymptomatic bacteriuria is present, or 3) there is no urine testing and no urinary symptoms. | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Patient self-efficacy | Stanford self-efficacy for managing chronic disease 6-item score (mean score range 1-10 with mean 1 indicating less self-efficacy) | 3 months |
| Patient satisfaction: Patient Global Impression of Improvement score |
Not provided
Inclusion Criteria:
Exclusion criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41628883 | Derived | Agrawal S, Ikpeama N, Koelper N, Dokras A, Harvie H, Hamm RF, Dutcher L, Arya LA. A Randomized Trial of a Texting Platform for Recurrent Urinary Tract Infections. Urogynecology (Phila). 2026 Mar 1;32(3):162-171. doi: 10.1097/SPV.0000000000001770. | |
| 39527705 | Derived | Arya LA, Agrawal S, Ikpeama N, Harvie H, Feldman RH, Dutcher L. Implementing a Digital Platform for Recurrent Urinary Tract Infections. Urogynecology (Phila). 2025 Mar 1;31(3):183-193. doi: 10.1097/SPV.0000000000001604. Epub 2024 Nov 11. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Apr 22, 2026 | May 13, 2026 | 8 | ||
| May 27, 2026 |
| ID | Term |
|---|---|
| D014552 | Urinary Tract Infections |
| ID | Term |
|---|---|
| D007239 | Infections |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
Not provided
Not provided
Not provided
Not provided
Not provided
Research assistant extracting data on primary and secondary outcomes will be masked to randomization
|
| Usual care | Other | • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers. |
|
Patient Global Impression of Improvement score (score range 1-7 with 1 indicating very much better)
| 3 months |
| Healthcare-related quality of life: EQ-5D-5L score | EQ-5D-5L score (score range 1-5 for each subscale with 1 indicating no problems) | 3 months |
| Healthcare-related quality of life: Recurrent UTI Impact Questionnaire score | Recurrent UTI Impact Questionnaire score (score range 0-10 for each subscale with 0 indicating strongly disagree) | 3 months |
| Healthcare utilization | Combined number of phone calls, secure messages, telehealth, and/or in-person visits per UTI episode | 3 months |
| Antibiotic prescriptions | Number of antibiotic prescriptions given for UTI episodes | 3 months |
| Patient medication compliance | Medication Adherence Self-Report Inventory score (score range 0-100 with 0 indicating no medication usage) | 3 months |
| Jun 22, 2026 |
| 9 |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |