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| ID | Type | Description | Link |
|---|---|---|---|
| 2027708 | Other Grant/Funding Number | McCance/ UAB |
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The goal of this clinical trial is to test the effects of 10 weeks of exercise on overall brain health, reduction in blood pressure, and the number of blood vessels in the back of the eyes in patients with hypertension and have a body mass index ≥ 25 kg/m2. The main question[s] it aims to answer are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High Intensity Interval Training (HIIT) exercise group, | Experimental | Participants will be asked to exercise independently 4 days/week for 10 weeks, following a high intensity interval training (HIIT) protocol. |
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| Moderate Intensity Training (MIT) exercise group | Experimental | Participants will be asked to exercise independently 4 days/week for 10 weeks, following a moderate intensity training (MIT) protocol. |
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| Control exercise group | Active Comparator | Participants will be advised to follow the American Heart Association (AHA) guidelines on exercise. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise Intervention to improve overall Brain Health | Behavioral | During each exercise session, the participant will be assigned to the HIIT or MIT exercise group and asked to ride the stationary bicycle for approximately 30-40 minutes, while wearing the heart rate monitor and recording the session on their smart phone application. For each exercise session, the Polar Beat application will record the time in each of four intensity "zones". The participant will receive training on how to use the outlined schedule during the initial supervised training session. |
| Measure | Description | Time Frame |
|---|---|---|
| Improved overall Brain Care Score metric. | The score is based on lifestyle categories on a scale of 0-21 where 21 is best. | 10 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pamela G. Bowen, PhD | University of Alabama at Birmingham | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UAB | Birmingham | Alabama | 35294 | United States |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D006973 | Hypertension |
| D050177 | Overweight |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D001519 | Behavior |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D044343 | Overnutrition |
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|
| D009748 |
| Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |