System to Evaluate the Risk of Lymph Node Metastasis Preoperatively in Cervical Cancer

Preoperative Scoring System to Predict the Risk of Lymph Node Metastasis in Cervical Cancer

The lymph node status is difficult to be assessed preoperatively, this study aimed to develop a scoring system for predicting the risk of LNM in cervical cancer patients before operation.

Lymph nodes metastasis (LNM) was proved to be a critical risk factor related to the survival to cervical cancer survival. However, preoperative pelvic magnetic resonance imaging (MR) or computed tomography (CT) tests are less sensitive to assess the risk of lymph node metastasis. PET-CT is too expensive and radiative to be widely used in clinical practice. A model was constructed based on clinical indicators to predict lymph node metastasis preoperatively, providing a reference for clinical treatment.

Inclusion Criteria:

• Clinical diagnosis of cervical cancer
• FIGO stage IB1-IIA1
• Undergone radical hysterectomy with pelvic lymphadenectomy
• Peformed pelvic MRI examination preoperatively

Exclusion Criteria:

• Had distant metastases diagnosed before or during the surgery
• Underwent neoadjuvant radiotherapy preoperatively
• Underwent neoadjuvant chemotherapy preoperatively
• Incomplete or inaccuratemedical records