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| Name | Class |
|---|---|
| Stanford University | OTHER |
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The investigators are examining whether the content of a visual scene impacts the antidepressant effects of light or if this impact is solely mediated by the intensity of the light.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Scene | Experimental | High fidelity scene of nature emitted from a monitor |
|
| Scrambled scene | Active Comparator | The same pixels that are used to create the scene in the alternate arm will be randomly scrambled on the monitor |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Light exposure | Other | Participants will be exposed to 15 minutes of each arm. They will be exposed twice and a randomized order (1/2/1/2 or 2/1/2/1) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in mood | Change in subjective mood as recored by the Positive and Negative Affect Schedule (PANAS). The PANAS ranges 10-50 on a positive mood scale (higher = more positive) and 10-50 on a negative mood scale (higher = more negative) | 15 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Change in fast brain electrical activity | Change in the beta power spectrum (12.5-30 Hz) of the electroencephalogram (brain waves, measured in microvolts) | 15 minutes |
| Change in systolic blood pressure (SBP) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| VA Palo Alto Health Care System | Palo Alto | California | 94304 | United States |
After completion of data collection, cleaning, and publication, all experimental data will be made available via Dryad
within three months of publication, no time limit
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| ID | Term |
|---|---|
| D003863 | Depression |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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Change in SBP (mm Hg) as measured by finger plethysmography
| 15 minutes |
| Change in heart rate variability (HRV) | Shift in the ratio of the power of low frequency to high frequency components in heart rate variability | 15 minutes |
| Change in sympathetic activity | Sympathetic activity will be imputed through the galvanic skin response (GSR). Change in skin conductance (the electrical activity on the skin) will be measured in microsiemens | 15 minutes |