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This is a single-center, randomized controlled study. The aim of this study is to compare the impact of left bundle branch area pacing versus traditional right ventricular pacing on the incidence of atrial fibrillation in patients with atrioventricular block.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| left bundle branch area pacing | Experimental |
| |
| right ventricular pacing | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| left bundle branch area pacing | Procedure | Left bundle branch area pacing(LBBAP) is a novel physiological pacing form for ventricular pacing. In patients received LBBAP, the pacing lead will be placed at left bundle branch area to achieve narrow paced QRS duration. |
| Measure | Description | Time Frame |
|---|---|---|
| the incidence of new-onset atrial fibrillation | within two years after device implantation |
| Measure | Description | Time Frame |
|---|---|---|
| all-cause mortality | within two years after device implantation | |
| hospitalization for heart failure | within two years after device implantation | |
| an device upgrade for heart failure |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Deyan Yang, PhD. | Contact | +86 (010)69155068 | swallow_sums@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Taibo Chen, PhD. | Peking Union Medical College Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chinese Academy of Medical Sciences & Peking Union Medical College, Peking Union Medical College Hospital | Beijing | Beijing Municipality | 100730 | China |
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| right ventricular pacing | Procedure | Right ventricular pacing is the traditional pacing modality for ventricular pacing. The pacing lead was placed in the apex or septum of right ventricle. |
|
| within two years after device implantation |
| alteration of quality of life score | within two years after device implantation |
| Improvement of left ventricular, right ventricular and left atrial function measured by echocardiography | within two years after device implantation |
| pacemaker-associated cardiomyopathy | within two years after device implantation |
| ID | Term |
|---|---|
| D054537 | Atrioventricular Block |
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D006327 | Heart Block |
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D000075224 | Cardiac Conduction System Disease |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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