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Determine the feasibility, acceptability and efficacy of an adapted digitally delivered CMAP (CMAP-SI) intervention (CAMI) compared to treatment as usual (TAU) for patients presenting with suicidal ideation.
The reported suicide rates in South Asia are high compared to the global average. These figures are likely to be an underestimate since suicide data from many LMICs such as Pakistan is lacking and what is available is not reliable (Jordans et al., 2014). According to an estimate, 5,000 to 7,000 suicides take place each year in Pakistan (Hafeez, 2016) and at least 10 to 20 suicide attempts happen for every suicide.
Mobile health is a novel and emerging field in psychiatric and psychological care and treatment of mental health difficulties, it involves the use of telecommunications to provide health care, support and intervention from a distance.
The proposed study will be carried out in two phases; Stage 1) adaptation of an already existing culturally adapted manual assisted problem solving intervention (CMAP) for patients with suicidal ideation presenting to primary care in Pakistan and further adaptation into a digital intervention.
Stage 2) feasibility Randomised Control trial.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention | Experimental | Digitally delivered CMAP intervention through App. CMAP is a manual-assisted intervention which has been adapted from a self-help guide called Life After Self-Harm based on the principles of Cognitive behavioral therapy (CBT). |
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| Standard Routine Care | No Intervention | Local medical, psychiatric and primary care services providing standard routine care to participant patients. Participants receiving an initial assessment along with TAU as ascertained by their treating doctor at the hospital or their primary care physician (general practitioner (GP) |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CAMI | Behavioral | Culturally Adapted manual-assisted problem solving training based Mobile Intervention (CAMI) for Suicidal Ideation. CMAP is a manual-assisted intervention which has been adapted from a self-help guide called Life After Self-Harm based on the principles of Cognitive behavioral therapy (CBT). This intervention is an evaluation of suicidal ideation, crisis skills, problem-solving and CBT techniques to manage emotions, negative thinking, interpersonal relationships and relapse prevention strategies. |
| Measure | Description | Time Frame |
|---|---|---|
| Suicide Ideation . | The BSI is a 19-item self-report instrument for detecting and measuring the current intensity of the patient's attitudes, behaviors and specificity of a patient's thoughts to die by suicide during the past week. Higher scores indicate greater severity of suicidal ideation | Change in scores from baseline to 3 and 6-month post-randomization |
| Measure | Description | Time Frame |
|---|---|---|
| Depression | Beck Depression Inventory (BDI), which is a 21-item scale measuring symptoms of depression. Higher scores on the scale indicate greater severity of depression. | Change in scores from baseline to 3 and 6-month post-randomization |
| Hopelessness |
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Inclusion Criteria:
Individuals (aged 18-64) screened and identified as having suicidal ideation
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Nasim Chaudhry, MRC Psych, FRC Psych, MD | Contact | 02135871845 | nasim.chaudhry@pill.org.pk | |
| Tayyeba Kiran, PhD | Contact | 03328262142 | tayyaba.kiran@pill.org.pk |
| Name | Affiliation | Role |
|---|---|---|
| Nasim Chaudhry, MRC Psych, FRC Psych | Pakistan Institute of Living and Learning | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Quetta Site | Quetta | Balochistan | Pakistan | |||
| Peshawar Site |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37525207 | Background | Husain N, Kiran T, Chaudhry IB, Williams C, Emsley R, Arshad U, Ansari MA, Bassett P, Bee P, Bhatia MR, Chew-Graham C, Husain MO, Irfan M, Khaliq A, Minhas FA, Naeem F, Naqvi H, Nizami AT, Noureen A, Panagioti M, Rasool G, Saeed S, Bukhari SQ, Tofique S, Zadeh ZF, Zafar SN, Chaudhry N. A culturally adapted manual-assisted problem-solving intervention (CMAP) for adults with a history of self-harm: a multi-centre randomised controlled trial. BMC Med. 2023 Jul 31;21(1):282. doi: 10.1186/s12916-023-02983-8. |
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| ID | Term |
|---|---|
| D059020 | Suicidal Ideation |
| D016728 | Self-Injurious Behavior |
| ID | Term |
|---|---|
| D013405 | Suicide |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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multicenter exploratory RCT
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Researcher conducting assessments will be masked to participant group allocation. This will be achieved by briefing participants and research staff in advance around maintaining masking.
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Beck Hopelessness Scale (BHS) (Beck, A and Steer, R, 1988) is a self-report instrument designed to measure three aspects of hopelessness: feelings about the future, loss of motivation and expectations during the past week. Higher scores indicate greater severity of hopelessness. |
| Change in scores from baseline to 3 and 6-month post-randomization |
| Health-related quality of life | Quality of life-EuroQoL (EQ-5D) (Brooks, R. and Group, E., 1996): This is a standardised instrument to measure health-related quality of life. It consists of a self-report questionnaire covering five dimensions of health (mobility, self-care, usual activities, pain/discomfort and anxiety/depression). Higher scores indicate better quality of life. | Change in scores from baseline to 3 and 6-month post-randomization |
| Client Service Receipt Inventory | Detailed description of the use of health services will be collected using the Client Service Receipt Inventory (CSRI) | Change in scores from baseline to 3 and 6-month post-randomization |
| Client Satisfaction Questionnaire | The Client Satisfaction Questionnaire (Attkisson, Zwick, & planning, 1982) is an 8 item measure of client satisfaction with services. Higher scores indicate greater satisfaction with the services received. | level of satisfaction at end of intervention i.e., 3-month post-randomization |
| Peshawar |
| KPK |
| Pakistan |
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| Lahore Site | Lahore | Punjab Province | Pakistan |
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| Multan Site | Multan | Punjab Province | Pakistan |
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| Rawalpindi Site | Rawalpindi | Punjab Province | Pakistan |
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| Hyderabad Site | Hyderābād | Sindh | Pakistan |
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| Karachi Site | Karachi | Sindh | 75350 | Pakistan |
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