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| ID | Type | Description | Link |
|---|---|---|---|
| 2023-A01101-44 | Other Identifier | IDRCB |
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Fighter pilots have to perform tasks requiring high mental workload during moderate-intensity acceleration phases (2 to 3G) that can last several minutes. When these accelerations are performed in the body axis (+Gz), they induce a redistribution of blood flow in the lower limbs associated with a decrease in cerebral blood flow, partially compensated by activation of the sympathetic nervous system (baroreflex).
The main hypothesis is that the effects of these prolonged accelerations, even of moderate intensity (<+4Gz), could impair pilots' ability to perform complex cognitive tasks, with potential consequences for flight safety and mission conduct.
Moreover, flight missions are often performed after sleep debt, which is known to induce cardiovascular responses, sympathetic nervous system activation and impaired mental performance.
The secondary hypothesis is that sleep debt (3h of time spent in bed) may increase the impairment of cognitive performance during prolonged acceleration.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A : Usual sleep *2 ; Deprivation *2 | V1->V3 id. V4 : Usual sleep and test series (easy; difficult; difficult) V5 : Usual sleep and test series (difficult; easy; easy) V6 : Sleep deprivation and test series (easy; easy; difficult) V7 : Sleep deprivation and test series (difficult; difficult; easy) |
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| Group B : Usual sleep ; Deprivation; Deprivation ; Usual sleep | V1->V3 id. V4 : Usual sleep and test series ( difficult; difficult ; easy) V5 : Sleep deprivation and test series (easy; difficult; difficult) V6 : Sleep deprivation and test series (difficult; easy; easy) V7 : Usual sleep and test series (easy ; easy ; difficult) |
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| Group C : Deprivation; Usual sleep ; Deprivation ; Usual sleep | V1->V3 id. V4 : Sleep deprivation and test series (easy; easy; difficult) V5 : Usual sleep and test series (difficult; difficult; easy) V6 : Sleep deprivation and test series (easy; difficult; difficult) V7 : Usual and test series (difficult; easy; easy) |
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| Group D : Deprivation ; Deprivation ; Usual sleep ; Usual sleep | V1->V3 id. V4 : Sleep deprivation and test series (difficult; easy; easy) V5 : Sleep deprivation and test series (easy; difficult; easy) V6 : Usual sleep and test series ( difficult; easy ; easy) V7 : Usual sleep and test series (easy ; difficult; difficult) |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Partial sleep deprivation | Other |
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| Measure | Description | Time Frame |
|---|---|---|
| Difference in average tracking accuracy on the simulator MATB-II depending on centrifuge acceleration (quantitative measurement) | MATB-II (Multi Attribute Task Battery) is a complex task simulator that mimics realistic tasks commonly performed by aircraft pilots during flight. Among these tasks, target tracking involves positioning a reticle at the center of the simulator's artificial horizon. The variance of the reticle's position as a function of the acceleration received in the centrifuge will be the primary outcome mesure in this study. This is a quantitative measure provided by the simulator. | Through study completion (26 months) |
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Inclusion Criteria:
Exclusion Criteria:
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The study population is composed of healthy subjects .
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sauvet | Contact | 178651275 | +33 | fabien.sauvet@intradef.gouv.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institut de Recherche Biomédicale des Armées | Recruiting | Brétigny-sur-Orge | 91223 | France |
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| ID | Term |
|---|---|
| D012892 | Sleep Deprivation |
| ID | Term |
|---|---|
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D009422 | Nervous System Diseases |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001523 | Mental Disorders |
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