An Observational Study of Local Relapse After High Grade Osteosarcoma

An Observational Study of Local Relapse After High Grade Osteosarcoma

multicenter retrospective and prospective study in patients with high-grade osteosarcoma

This is a multicenter retrospective and prospective study that will analyze all cases with of diagnosis of local relapse in high-grade osteosarcoma from 01 January 1980 and all new cases referring to each participant site.

Inclusion Criteria:

• Patients who experienced LR as first event of recurrence after treatment for localized high-grade osteosarcoma of bone, including cases with synchronous lung metastases
• Adequate patient compliance to follow-up visits
• Written informed consent prior to any study-specific analysis and/or data collection
• No age limits

Exclusion Criteria:

• Cases of LR demonstrated after > 3 months after metastatic disease
• Impossibility to ensure adequate compliance