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Participants will complete a functional MRI to evaluate brain activation, functional connectivity, and behavioral performance immediately before and after a training program (approximately 30 minutes). The training program will comprise of integrate neuromuscular (agility, dynamic postural stability, shuffling, rapid acceleration/deceleration, plyometrics, lateral shuffle, and core stability) and cognitive (reaction time, processing speed, task switching, decision-making, and working memory) challenges.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Physically active females | Experimental | Healthy active females between 18 and 25 |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Motor-Cognitive Training Program | Other | The training will incorporate cognitive tasks which focus on reaction time, processing speed, working memory, cognitive flexibility, and inhibitory control using visual stimuli on a screen or through sensors which illuminate using LED lights. These cognitive tasks will be performed while also executing physical performance tasks that challenge static and dynamic postural stability, lateral movement, agility, and other movement patterns. The training session will last approximately 30 minutes and participants will complete up to 5 exercises |
| Measure | Description | Time Frame |
|---|---|---|
| Change in brain activation | During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The level of brain activation during the task will be captured and reported. | 2 hours, pre-training session and immediately post-training session |
| Change in functional connectivity | The participant will complete a resting-state functional MRI scan in which they will lay still in the scanner. No task is performed during this scan. Functional connectivity (functionally related regions of the brain that are co-activated) during the scan will be captured and reported. | 2 hours, pre-training session and immediately post-training session |
| Change in reaction time | During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The reaction time in milliseconds will be captured. The change in reaction time from pre to post training session will be reported. | 2 hours, pre-training session and immediately post-training session |
| Change in accuracy | During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The percent of correct responses (accuracy) will be captured. The change in accuracy from pre to post training session will be reported. | 2 hours, pre-training session and immediately post-training session |
| Measure | Description | Time Frame |
|---|---|---|
| Demographic/Injury History Form | The demographic and injury history form is designed to capture: 1) information about the participant including age, height, weight, race, ethnicity, 2) information related to sports participation, and 3) information related to past injuries or medical conditions which are relevant to the study. | Once, pre-training |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ke'La H Porter, MS | University of Kentucky | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Kentucky | Lexington | Kentucky | 40506 | United States |
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| ID | Term |
|---|---|
| D001265 | Athletic Injuries |
| ID | Term |
|---|---|
| D014947 | Wounds and Injuries |
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| Defense Veterans Pain Rating Scale | The Defense Veterans Pain Rating Scale is a valid 5-item scale to assess pain magnitude and pain interference. This scale ranges from 0 to 10, 0 indicating no pain/interference and 10 indicating as bas as it could be/complete interference. | Once, pre-training |
| Modified Disablement In Physically Active Scale | 16-item patient-reported outcome instrument that assesses physical and psychosocial status.This scale ranges from 0 to 4, 0 indicating no problem and 4 indicating severe. | Once, pre-training |
| NASA Physical Activity Survey | This survey asks individuals to self-report their general physical activity over the past week. This survey ranges from 0 to 10, 0 indicating sedentary and 10 indicating high physical activity. | Once, pre-training |
| Heart rate | Heart rate will be monitored with a noninvasive heart rate monitor that will be worn by the participant around the chest at the level of the xiphoid process. Resting heart rate will be collected prior to the start intervention then monitored and recorded throughout the training session. | 35 minutes, during the training session |
| Average reaction time during the intervention | Average reaction time in milliseconds will be captured during the exercises via light sensors. | 30 minutes, during the training session |
| Misses during the training session | The number of misses will be captured during the exercises via light sensors. A miss is considered when they deactivate the wrong sensor or don't deactivate the sensor quickly enough. | 30 minutes, during the training session |
| Hits during the training session | The number of hits will be captured during the exercises via light sensors. A hit is considered when they deactivate the correct sensor. | 30 minutes, during the training session |
| Number of errors during the training session | The number of errors will be captured during the exercises by visual observation. An error occurs when they do not complete they exercise correctly. | 30 minutes, during the training session |
| Rate of perceived exertion | After each exercise the participant will be asked to rate their perceived exertion on a scale from 6 to 20, 6 indicating low perceived exertion and 20 indicating high perceived exertion | 30 minutes, during the training session |
| Perceived cognitive difficulty | After each exercise the participant will be asked to rate their perceived cognitive difficulty on a scale from 1 to 10, 1 indicating low cognitive challenge and 10 indicating high cognitive challenge | 30 minutes, during the training session |