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The purpose of the study is to characterize the challenges to physical activity and exercise for HS patients and design an exercise program (EP) with evidence-based techniques and examine its outcome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Home Exercise EP Group | Experimental | Participants in this group will follow an at home personalized EP for up to 12 weeks. |
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| Short EP Group | Active Comparator | Participants in this group will be enrolled in the short EP program. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Home Exercise Program | Behavioral | Participants will perform a minimum of one exercise from each of the targeted muscle groups at a frequency of every other day, for a total of 3-4 days a week of exercise with a rest day. The entire strengthening exercise routine should take approximately 25-30 minutes to perform, including rest periods. Each muscle grouping of exercises is designed to progress from minimal muscle effort required to moderate to maximal effort. Participants will use a video to perform the exercises as well as a handout with specific instructions. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Functional Strength/Endurance as Measured by 30-second chair-stand test | Determines how many times a person can rise from a chair and sit down again in 30 seconds while keeping their arms crossed over their chest. The test will assess lower body strength and endurance and will be reported using a composite score of the number of times completed. | Baseline and up to 12 weeks |
| Change in Functional Strength/Endurance as measured by six-minute walk test | Six-minute walk measures overall functioning capacity, and lower body muscle strength/ endurance, with a composite score reported in meters. | Baseline and up to 12 weeks |
| Change in Functional Strength as measured by hand grip strength test | It is a measure of upper body muscular strength measured in kilograms. | Baseline and up to 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life impairment as measured by the DLQI | Dermatology Life Quality Index (DLQI) has a total score ranging from 0 to 30 with the lower score indicating higher health related quality of life. | Baseline, up to 12 weeks |
| Quality of life impairment as measured by the HiSQOL |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hadar Lev-Tov, MD | University of Miami | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Miami | Miami | Florida | 33125 | United States |
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| ID | Term |
|---|---|
| D017497 | Hidradenitis Suppurativa |
| ID | Term |
|---|---|
| D017192 | Skin Diseases, Bacterial |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
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| Short Exercise Program | Behavioral | Participants in this group will attend one in-person visit expected to last about 60 minutes. The clinic visit will consist of standard of care procedures and tests for individuals with mild-to-severe HS . |
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Hidradenitis Suppurativa Quality of Life (HiSQOL) has a total score ranging from 0 to 68 with the lower score indicating higher health related quality of life. |
| Baseline, up to 12 weeks |
| Change in Physical activity as measured by the International Physical Activity Questionnaire (IPAQ) | IPAQ assesses 3 types of physical activity undertaken across the 4 domains- leisure time physical activity; domestic and gardening (yard) activities; work-related physical activity; transport-related physical activity- in the previous 7 days. The 3 types of activity assessed are walking, moderate-intensity activities and vigorous-intensity activities. The result s is not reported in scales. Computation of the total score for the IPAQ requires summation of the duration (in minutes) and frequency (days) of the 3 types of activities across the 4 domains. Higher result indicates higher physical activity in the last 7 days | Baseline, up to 12 weeks |
| Change in Level of Activity as measured by the average number of steps daily | Average number of steps daily will be measured with a pedometer and will be reported. | Baseline, up to 12 weeks |
| Change in Severity of HS score using the IHS-4 | The International Hidradenitis Suppurativa Severity Score System (IHS4) measures HS severity as mild (0-3), moderate (4-10), severe (≥11). Higher score indicate increased severity. | Baseline, up to 12 weeks |
| Average pain as assessed by the Numerical Rating Scale (NRS) | The average pain will be measured using the NRS with scores ranging from 0-10 with the higher score indicating more severe pain. | Up to 8 weeks |
| D012874 | Skin Diseases, Infectious |
| D013492 | Suppuration |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D016575 | Hidradenitis |
| D013543 | Sweat Gland Diseases |