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The aim of this study is to evaluate the effect on urine color by adding household bleach to fresh urine sample among pediatric UC subjects treated with 5ASA
The aim of this study is to evaluate the effect on urine color by adding household bleach to fresh urine sample among pediatric UC subjects treated with 5ASA.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pediatric UC subjects treated with 5ASA compunds | Active Comparator | Each subject will provide a fresh urine sample in an empty sterile plastic cup. Urinalysis will be performed to check for macro- or micro-hematuria or signs of infection. We will take 10mL of the urine sample and add 1mL of transparent (colorless) household bleach (≤5% sodium hypochlorite). The color of the urine before and 5 minutes after adding the bleach will be recorded. |
|
| Pediatric UC subjects not treated with 5ASA compunds (any other treatments is allowed) | Placebo Comparator | Each subject will provide a fresh urine sample in an empty sterile plastic cup. Urinalysis will be performed to check for macro- or micro-hematuria or signs of infection. We will take 10mL of the urine sample and add 1mL of transparent (colorless) household bleach (≤5% sodium hypochlorite). The color of the urine before and 5 minutes after adding the bleach will be recorded. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Adding household bleach to urine sample | Other | Adding household bleach to urine sample |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change is urine color | Following the addition of 1mL of 5% household bleach to a 10mL of each subject's urine, we will visually look for color change to red or orange within 5 minutes. Urine changing color to red or orange will be marked as a positive response to the bleach, which would fulfill the primary outcome. | 5 minutes |
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Inclusion Criteria:
1. UC patients in remission
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Eyal Zifman, MD | Meir Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Meir Medical Center | Kfar Saba | 4464402 | Israel |
According to instructions from our IRB the study's IPD is not to be shared. Specific requests may be sent after the study's completion and will be considered by the IRB .
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jun 4, 2024 | |
| Reset | Sep 26, 2024 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jun 4, 2024 | Sep 26, 2024 |
| ID | Term |
|---|---|
| D003093 | Colitis, Ulcerative |
| D006417 | Hematuria |
| ID | Term |
|---|---|
| D003092 | Colitis |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| D015212 |
| Inflammatory Bowel Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D014555 | Urination Disorders |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |