The Effect of Home-Based Walking Program on Peripheral Neuropathy, Fatigue and Quality of Life

The Effect of Home-Based Walking Program on Peripheral Neuropathy, Fatigue and Quality of Life in Patients Receiving Taxane and Platinum-Based Chemotherapy

The study aims to evaluate the effect of home-based walking program on peripheral neuropathy, fatigue and quality of life in patients receiving taxane and platinum-based chemotherapy.

The study was designed as a randomized controlled trial. This study will be carried out with a total of 88 cancer patients receiving taxane and platinum-based chemotherapy, 44 of whom were in the intervention group and 44 in the control group, whose treatment was started in Akdeniz University Hospital."Home Based Walking Program" will be applied to the patients in the intervention group for 8 weeks.Within the scope of the Home-Based Walking Program, face-to-face patient education, patient education booklet, sending text messages, face-to-face and telephone counseling were planned.

Patient Identification Form, International Physical Activity Questionnaire (IPAQ- Short Form), National Cancer Institute (NCI) -CTCAE v5.0 Toxicity Criteria, Cancer Fatigue Scale, EORTC QLQ-CIPN20 (Quality of Life Chemotherapy-Induced Peripheral Neuropathy) and EORTC QLQ-C30 (Quality of Life Scale), Interview Form will be used to collect data.

İnclusion Criteria

• 18 Years and older (Adult, Older Adult )
• Turkish speaking-understanding ability and literate.
• Orientation (person, place, time)
• Receiving taxane and platinum-based chemotherapy treatment (monotherapy or combined).
• Receiving chemotherapy treatment for the first time.
• The primary medical diagnosis is cancer (breast cancer, colorectal cancers and other cancers).
• Not having health problems that prevent walking.
• Agreeing to participate in the research.

Exclusion Criteria

• Being bone and brain metastases
• Being peripheral neuropathy due to reasons other than chemotherapy (such as chronic disease, diabetes mellitus, nutritional disorders)
• Skin sensitivity on the hands and feet
• Having cardiovascular, pulmonary, musculoskeletal, or psychological disorders that limit exercise or mobility
• Being in another supportive program
• Being in the very active category according to the "International Physical Activity Scale (IPAQ- Short Form)"
• Being a severity of more than 4 points according to the "Modified Borg Scale (MBS)"
• Being a score of 2 and above according to the "ECOG Performance Scale"