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| Name | Class |
|---|---|
| National Institute on Aging (NIA) | NIH |
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This trial will examine scheduled exposure to bright light in the morning and afternoon as a countermeasure to sleep fragmentation in older individuals with mild cognitive impairment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard of care | Active Comparator | One hour of daily bright light exposure beginning one hour after wake time. |
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| Stepped care | Experimental | One hour of daily bright light exposure in the afternoon |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Light therapy | Behavioral | One hour of exposure to bright light, either by being outdoors or with a phototherapy lamp if indoor |
|
| Measure | Description | Time Frame |
|---|---|---|
| Sleep fragmentation | 24 hour sleep wake patterns will be quantitated with a non-parametric measure, intradaily variation | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Cognition | Performance on the WAIS-4 | 6 months |
| Mood | Geriatric Depression Scale, range: 0-15 with higher scores being associated with greater depressive symptomatology |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Renske Lok, PhD | Contact | rlok@stanford.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stanford University | Redwood City | California | 94063 | United States |
After completion of study and publication of data, deidentified IPD will be uploaded to Dryad with documentation. Analytic code will be shared with Github
within six months after publication; no restrictions on duration of availability
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| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| D019964 | Mood Disorders |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D010789 | Phototherapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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| 6 months |