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Explore the role of Inflammation and coagulation factors in cerebrospinal fluid for predicting persistent cerebral edema after subarachnoid hemorrhage
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Inflammatory factors and coagulation factors level in cerebrospinal fluid after subarachnoid hemorrhage | Diagnostic Test | Inflammatory factors and coagulation factors level in cerebrospinal fluid will be tested by ELISA kits. |
| Measure | Description | Time Frame |
|---|---|---|
| Cerebral edema after subarachnoid hemorrhage | Cerebral edema after subarachnoid hemorrhage will be determined by the SEBES score. SEBES 0-2 is mild edema; SEBES 3-4 is severe edema. | At 3 and 7days after SAH onset |
| Outcome at 3 months after subarachnoid hemorrhage | Outcome will be determined by the modified Rankin Score (mRS). mRS 0-2 is favorable outcome; mRS3-5 is poor outcome. | 3 months after subarachnoid hemorrhage |
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Inclusion Criteria:
Exclusion Criteria:
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Subarachnoid hemorrhage patients admitted to our neurosurgery department with modified Fisher Scale 3-4, with a confirmed radiographic diagnosis. Age range from 20-80.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yuanjian Fang, M.D | Contact | 86-18768109541 | sandman0506@zju.edu.cn | |
| Sheng Chen, M.D | Contact | 86-13645814323 | saintchan@zju.edu.cn |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Second affiliated hospital of Zhejiang University, School of Medicine | Recruiting | Hangzhou | Zhejiang | 310000 | China |
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| ID | Term |
|---|---|
| D007249 | Inflammation |
| D013927 | Thrombosis |
| D006474 | Hemorrhagic Disorders |
| D001929 | Brain Edema |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D016769 | Embolism and Thrombosis |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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