Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This is a multicenter, retrospective clinical study, in patients with brucellosis, to analyze the clinical characteristics, complications, and the impact of different treatment options on long-term prognosis of patients with brucellosis. All hospitalized patients diagnosed with brucellosis between 2016 and 2021 were included from the electronic medical record systems of eight centers, collecting demographics, hospitalization information, clinical information, laboratories, imaging studies, treatment regimens, and disease outcome and other information.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Clinical characteristics | The electronic medical record system was used to collect patients' symptoms from baseline (admission) to 24 months, including initial symptoms, constitutional symptoms and signs [fever (maximum temperature, duration), hyperhidrosis, muscle/joint soreness, fatigue, hepatomegaly, splenomegaly, testicular enlargement, oophoritis, lymphadenopathy (location and size), others]. | 2 year |
| Complication rate | Electronic medical record system was used to collect the complications of patients from baseline (admission) to 24 months, and the incidence of complications within 2 years was calculated. Complications include osteoarticular system (sacroiliitis, spondylitis, peripheral arthritis, osteomyelitis, bone destruction, etc.) that may be related to brucellosis, Genitourinary system (orchitis, epididymitis, oophoritis, glomerulonephritis, renal abscess, etc.), central nervous system (peripheral neuropathy, meningoencephalitis, mental symptoms, cranial nerves, chorea, etc.), skin (maculopapular rash, Cyst, Stevens-Johnson syndrome, etc.), respiratory system (pleural effusion, pneumonia, etc.), blood system (leukocyte increase or decrease, platelet deficiency, etc.), cardiovascular system (endocarditis, vasculitis, myocarditis wait). Diagnostic tests for complications include laboratory tests (blood routine, etc.), echocardiography, imaging tests (X-ray, ultrasound, high-resolution CT) | 2 year |
| Measure | Description | Time Frame |
|---|---|---|
| Survival rate | The 1-year survival rate and 2-year survival rate were calculated. | 1 year,2 years |
| Disease outcome (cured, improved, not cured, progress, relapse, death) | The electronic medical record system was used to collect the disease outcomes of patients from baseline (admission) to 24 months. |
Not provided
Inclusion Criteria:
Age and gender are not limited;
Discharged patients diagnosed with brucellosis
Specific reference to the People's Republic of China's health industry standard "Diagnosis for brucellosis" (WS269-2019) diagnosed as a patient with brucellosis, that is, the patient meets a suspected or clinically diagnosed case and passes the confirmatory test mentioned below at the same time Either to prove:
Volunteer to join this study.
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Hospitalized patients diagnosed with Brucellosis from 8 centers in Hubei Province, China.
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Guangshui First Peoples Hospital | Guangshui | Hubei | China | |||
| Huanggang Central Hospital |
Not provided
| ID | Term |
|---|---|
| D002006 | Brucellosis |
| ID | Term |
|---|---|
| D016905 | Gram-Negative Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
Not provided
Not provided
Not provided
Not provided
Not provided
| 2 year |
| Etiological characteristics (B.melitensis [1, 2, 3 subtypes], B.abortus[1-9 subtypes], B.suis [1-5 subtypes], B.canis) | Etiologic characteristics were collected from baseline (admission) through 24 months with the use of an electronic medical record system. The distribution of pathogens was analyzed, and the relationship between different pathogenic characteristics and long-term prognosis (disease outcome) was evaluated. | 2 year |
| Number of patients with severe brucellosis (ICU number) | The electronic medical record system was used to collect the proportion of patients admitted to ICU from baseline (admission) to 24 months, and the proportion of patients admitted to ICU was calculated. | 2 year |
| antimicrobial therapy | The electronic medical record system was used to collect the treatment options of patients from baseline (admission) to 24 months, and the impact of different treatment options on prognosis (disease outcome) was evaluated. | 2 year |
| Hospital costs | The electronic medical record system was used to collect the hospitalization expenses of patients, and the average hospitalization cost was calculated. | 2 year |
| Huanggang |
| Hubei |
| China |
| People's Hospital of Luotian County | Huanggang | Hubei | China |
| People's Hospital of Macheng city Affiliated Hospital of Hubei Univerciy of science and technology | Macheng | Hubei | China |
| Qianjiang Central Hospital | Qianjiang | Hubei | China |
| Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology | Wuhan | Hubei | 430030 | China |
| Xianning Central Hospital | Xianning | Hubei | China |
| Yichang Third Peoples Hospital | Yichang | Hubei | China |