C-Reactive Protein/Albumin Ratio and Acne Vulgaris | NCT06004583

Studies
C-Reactive Protein/Albumin Ratio and Acne Vulgaris

NCT06004583

Sponsor

Ataturk University

Status

Completed

Last Update Posted

Aug 22, 2023Actual

Enrollment

96Actual

Phase

Not provided

Conditions

Acne Vulgaris

Interventions

Biochemical blood analysis

Countries

Turkey (Türkiye)

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Aug 2023

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jan 5, 2022Actual

Primary Completion Date

Feb 2, 2023Actual

Completion Date

May 1, 2023Actual

First Submitted Date

Aug 16, 2023

First Submission Date that Met QC Criteria

Aug 21, 2023

First Posted Date

Aug 22, 2023Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Aug 21, 2023

Last Update Posted Date

Aug 22, 2023Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Not provided

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

Objective: Acne vulgaris, an inflammatory disease, was investigated in this study with the claim that C-reactive protein (CRP) / albumin ratio and some hematological parameter ratios have the potential to be used as inflammatory markers to monitor disease severity and prognosis.

Methods: A descriptive cross-sectional study was conducted with two groups of patients aged 18-65 years, 61 patients diagnosed with acne vulgaris and 35 healthy control patients, and routine hemogram and biochemical parameters were compared. The Global Acne Severity Index was used to determine the severity of acne vulgaris.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

96Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Acne group		Acne Vulgaris Diagnosed Patients	Diagnostic Test: Biochemical blood analysis
Control group		Healthy participants	Diagnostic Test: Biochemical blood analysis

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Biochemical blood analysis	Diagnostic Test	Serum CRP and albumin levels	Acne group Control group

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
CRP/albumin ratio	Statistical difference between groups	3 months

Secondary Outcomes

Measure	Description	Time Frame
Usage of CRP/albumin ratio as a Biomarker	New detection of CRP/albumin ratio as a new biomarker in the Acne patients	3 months

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Acne vulgaris patients diagnosed by a dermatologist
Healthy participants without acne
18-40 years of age
Voluntary participation

Exclusion Criteria:

Aged below18 or above 40 years
Not voluntarily participated patents
Pregnants, breast milked mothers, emergency situations

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

40 Years

Standard Ages

Adult

Study Population

Acne vulgaris patients and control healthy individuals

Sampling Method

Probability Sample

Condition Browse Module

MeSH Terms

ID	Term
D000152	Acne Vulgaris

Ancestor Terms

ID	Term
D017486	Acneiform Eruptions
D012871	Skin Diseases
D017437	Skin and Connective Tissue Diseases
D012625	Sebaceous Gland Diseases

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Browse Branches

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