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clinical efficacy of autologous stromal vascular fraction SVF,for inflammatory and degenerative conditions of the knees
to evaluate the clinical effectiveness of point of care autologous adipose derived stromal vascular fraction (SVF) alone or in combination with exosomes,for inflammatory and degenerative conditions of the knees.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| knee osteoarhritis | Experimental | patients with grade 2 and above chondromlacia as well as all grades of osteoarhtritis |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| stromal vascular fraction injection in the osteoarthritic knee | Procedure | stromal vascular fraction harvested from mid abdominal wall under sedation and seperated from fat using mechanical centrifugation .injection of 5 cc of the SVF in the affected knee. |
| Measure | Description | Time Frame |
|---|---|---|
| change in pain level | visual analog scale 0-10 ( 10 being worst) | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| percentage cartilage thickness change | as measured by MRI | 2 years |
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Inclusion Criteria:
knee osteoarthritis any grade
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Amer Mansour, MD | Contact | +971502983375 | dramermansour@gmail.com | |
| mazen sawaf, MD | Contact | +971504545266 | drmax@novomed.com |
| Name | Affiliation | Role |
|---|---|---|
| DHA DHA | dubai health autority | Study Director |
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| Label | URL |
|---|---|
| cell surgical network | View source |
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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investigator is blinded to clinical and radiological assessments .
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| D012216 |
| Rheumatic Diseases |