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Resting tremors associated with Parkinson's disease (PD) remains difficult to quantify and track during disease progression. This study propose to explore the rhythmicity of distal muscle contractions in the upper limb to characterize resting tremor and discriminate it from cerebellar tremor (CT) based on the frequency spectrum of the EMG signal.
This retrospective study analyzed surface EMG recordings of wrist flexor-pronators and extensor-supinators from patients with PD or CT bilaterally in five 10-second conditions: rest with contralateral motor distraction, symmetrical arms extended forward posture with hands pronated, semi-pronation, supination, and elbows flexed with hands pronated. The rhythmicity index (RI) is calculated from the ratio of the area of the maximum power peak to the total area of the spectrum between 1.5-12Hz.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Tremor of rest | Patient with a diagnosis of Parkinson's disease and who performed surface EMG recordings of wrist flexor-pronators and extensor-supinators analysis in Laboratories |
| |
| Cerebellar tremor | Patient with a diagnosis of cerebellar tremor and who performed surface EMG recordings of wrist flexor-pronators and extensor-supinators analysis in Laboratories |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EMG in wrist flexor-pronators and extensor-supinators | Diagnostic Test | The subject is asked to perform a series of tasks: resting posture, symmetrical posture arms forward, unilateral distal movement. Each task lasts 10 seconds. |
| Measure | Description | Time Frame |
|---|---|---|
| rhythmicity index | The rhythmicity index (RI) is calculated from the ratio of the area of the maximum power peak to the total area of the spectrum between 1.5-12Hz. | 10 seconds |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with Parkinson's disease or cerebellar tremor diagnosis.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Emilie Hutin, PhD | Contact | +33149812549 | emilie.hutin@aphp.fr | |
| Emilie Hutin | Contact | emilie.hutin@aphp.fr |
| Name | Affiliation | Role |
|---|---|---|
| Emilie Hutin | Henri Mondor University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Laboratoire Analyse et Restauration du Mouvement | Recruiting | Créteil | France |
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| ID | Term |
|---|---|
| D002528 | Cerebellar Neoplasms |
| D014202 | Tremor |
| D000987 | Antisocial Personality Disorder |
| ID | Term |
|---|---|
| D015192 | Infratentorial Neoplasms |
| D001932 | Brain Neoplasms |
| D016543 | Central Nervous System Neoplasms |
| D009423 | Nervous System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D002526 | Cerebellar Diseases |
| D020820 | Dyskinesias |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010554 | Personality Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D004576 | Electromyography |
| ID | Term |
|---|---|
| D004568 | Electrodiagnosis |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D009213 | Myography |
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